10318-18-0

Basic information

• Product Name: DL-Cysteine hydrochloride
• Synonyms: DL-Cysteine hydrochloride hydrate,99%;2-Amino-3-mercaptopropanoic acid Hydrochloride;DL-Cysteine HC1;H-DL-Cys-OH·HCl DL-Cysteine hydrochloride;H-DL-Cys.HCl;2-Amino-3-mercaptopropanoicacid;3-Mercaptoalanine;52-89-1dl-cysteinehydrochloride
• CAS NO: 10318-18-0
• Molecular Formula: C₃H₈NO₂S*Cl
• Molecular Weight: 157.62
• EINECS: 233-698-2
• Product Categories: Pharmaceutical Intermediates;Amino Acids;Biochemicals and Reagents
• Mol File: 10318-18-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 109-112 °C
• Boiling Point: 293.9 °C at 760 mmHg
• Flash Point: 131.5 °C
• Appearance: white crystals or crystalline powder
• Vapor Pressure: 2.47E-07mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: H2O: soluble
• Water Solubility: soluble
• Sensitive: Air Sensitive & Hygroscopic
• BRN: 4150473
• CAS DataBase Reference: DL-Cysteine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: DL-Cysteine hydrochloride(10318-18-0)
• EPA Substance Registry System: DL-Cysteine hydrochloride(10318-18-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• RTECS: HA2200000
• F: 3-10-23
• Hazardous Substances Data: 10318-18-0(Hazardous Substances Data)

Usage

Chemical Properties

white crystals or crystalline powder

Uses

DL-Cysteine hydrochloride is used in cell culture. It is also used in photochemical vascular injury (performed using dl-cysteine hydrochloride along with other components). It may be used in the preparation of DL-4-carboxy-3-formyl-2,2,-dimethylthiazolidine.

Biochem/physiol Actions

DL-Cysteine is a racemic mixture of the proteinogenic amino acids L-cysteine and the non-proteinogenic D-cysteine. DL-Cysteine is used as an organic reagent and in comparative physicochemical analysis of processes such as crystallization.

Purification Methods

Crystallise the salt from hot 20% HCl and dry it under vacuum over P2O5. It also crystallises from EtOH with m 175o (hydrate). When crystallised from absolute EtOH or EtOH/Et2O, it has m 140-141.5o (anhydrous). [Rurner & Voitle J Am Chem Soc 72 628 1950, Albert Biochem J 50 690 1953, Beilstein 4 IV 3145.]

InChI:InChI=1/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2

Upstream product

• 56-89-3 cysteine disulfide 
• 66871-99-6 2,2-Dimethylthiazolidin-4-carbonitril 
• 116179-35-2 2-Phenyl-2-thiazolin-4-carbonsaeure-hydrochlorid 
• 116077-28-2 2-Phenyl-2-thiazolin-4-carboxamid 

Downstream Products

• 1265908-22-2 2-(4-hydroxy-3-methoxyphenyl)-1,3-thiazolidine-4-carboxylic acid 
• 98379-74-9 (3aS,4R,6aS,7R,10S,10aR)-10-(acetyloxy)octahydro-4,7-dimethyl-8H,10H-furo[3,2-i][2]benzopyran-8-one 
• 82003-85-8 (3R,3aS,6R,6aS,8R,9S,10aS,10bR)-octahydro-8-hydroxy-3,6,9-trimethyl-10aH-9,10b-epoxypyrano[4,3,2-jk][2]benzoxepin-2(3H)-one 
• 79173-74-3 2-(5-methyl-2-hydroxyphenyl)-thiazoline-4-carboxylic acid sodium 
• 73978-41-3 2,4-diamino-6-(hydroxymethyl)pteridine hydrochloride 
• 92678-32-5 N,S-dibenzoylcysteine 
• 945-24-4 2,4-diamino-6-(hydroxymethyl)pteridine 
• 207599-68-6 2-amino 3-(2,4-dichlorobenzylthio) propionic acid 
• 17087-36-4 2-(1,2,3,4-tetrahydroxybutyl)thiazolidine-4-carboxylic acid 
• 444-27-9 L-thiaproline 
• 181528-64-3 9α-acetoxy-10β-methoxyartemethin-I 
• 174097-70-2 3α-hydroxy-12β-methoxyartemethin-III 
• 25683-09-4 3-(triphenylmethylthio)-alanine 
• 3411-58-3 L-cysteine ethylester 

Relevant articles and documents

REDUCTIVE CLEAVAGE OF SULFUR OF SULFUR-SULFUR BONDS WITH SODIUM HYDROGEN TELLURIDE

Sodium hydrogen telluride is shown to be an effective reagent for reduction of alkyl, aryl and functionally substituted disulfides to thiols in good yield under mild conditions.Organic thiosulfites (Bunte salt) also give thiols through the corresponding disulfide on reaction with sodium telluride.

Einfache Synthese von racemischem Cystein

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