Welcome to LookChem.com Sign In|Join Free
  • or

638-23-3

Post Buying Request

638-23-3 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
Carbocisteine
Cas No: 638-23-3
No Data 25 Kilogram Metric Ton/Day HANGZHOU CLAKE BIOTECH CO.,LTD Contact Supplier
High Purity S-Carboxymethyl-L-Cysteine
Cas No: 638-23-3
No Data 1 Kilogram 15000 Kilogram/Year Siwei Development Group Ltd. Contact Supplier
S-Carboxymethyl-L-cysteine Manufacturer/High quality/Best price/In stock
Cas No: 638-23-3
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
Carbocisteine ( 3-Carboxymethylthio-L-alanine)
Cas No: 638-23-3
No Data 1 Kilogram 500000 Kilogram/Year Sinoway Industrial Co., Ltd. Contact Supplier
High quality S-Carboxymethyl-L-Cysteine supplier in China
Cas No: 638-23-3
No Data 1 Kilogram 30 Metric Ton/Month Simagchem Corporation Contact Supplier
High purity 638-23-3 Carbocysteine(SCMC)
Cas No: 638-23-3
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Carbocysteine
Cas No: 638-23-3
USD $ 1.0-2.0 / Metric Ton 1 Metric Ton 100 Metric Ton/Week Hebei yanxi chemical co.,LTD. Contact Supplier
Good quality Carbocistein//638-23-3
Cas No: 638-23-3
No Data 1 Kilogram 10 Metric Ton/Month Hefei TNJ chemical industry co.,ltd Contact Supplier
High Quality Food Grade S-Carboxymethyl-L-Cysteine 638-23-3 HACCP Manufacturer
Cas No: 638-23-3
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Carbocistein
Cas No: 638-23-3
No Data 1 Kilogram 20 Metric Ton/Month Henan Allgreen Chemical Co.,Ltd Contact Supplier

638-23-3 Usage

Uses

carbocysteine is an amino acid. It can be used to help control sebum production.

Safety Profile

contact. A riot control agent. When heated

Brand name

Loviscol (Wyeth-Ayerst); Mucofan (Wyeth-Ayerst).

Manufacturing Process

There were placed 120g of L-cysteine (0.5 mol) in a 2 liter three-necked flask equipped with a stirrer thermometer and methanol/dry ice cooling and 1.5 liters of liquid ammonia were allowed to enter at -40°C. Then there were added under continuous cooling 50 g (2.17 mols) of sodium metal in portions of 1 to 2 g during the course of one hour. The end of the reaction was recognized by the continuation of the blue color. After the end of the reaction the excess sodium was destroyed by the addition of ammonium chloride and the ammonia vaporized at normal pressure. The residue was taken up in 500 ml of water and concentrated in a vacuum to 200 ml in order to remove residual ammonia, and again treated with 300 ml of water. The entire operations were carried out under a nitrogen atmosphere.The aqueous solution of the disodium salt of L-cysteine obtained is then reacted at 20°C to 30°C under a nitrogen atmosphere in the course of 30 minutes with stirring with a solution of 104 g of chloroacetic acid (1.1 mols) and 4 g of sodium pyrosulfite in 200 ml of water. It is also allowed to post react for 15 minutes at 20°C, the solution clarified over activated carbon and the filtrate treated with 90 ml of concentrated hydrochloric acid to a pH of 2.5.Thereby the S-carboxymethyl-L-cysteine precipitates out in crystalline form. The product is filtered off with suction, well stirred in 500 ml of water, again filtered with suction and dried in a vacuum at 70°C. The yield is 92% based on L-cysteine.

Originator

Rhinathiol,Kramer,Switz.

Uses

Labeled Carbocisteine, intended for use as an internal standard for the quantification of Carbocisteine by GC- or LC-mass spectrometry.

Chemical Properties

white to slightly off-white amorphous powder

Uses

Carbocisteine is a mucolytic agent used in the treatment of respiratory disorders ranging from the influenza virus infection to chronic obstructive pulmonary disease (COPD).

Therapeutic Function

Mucolytic, Expectorant, Nasal antiinfective
InChI:InChI=1/C5H9NO4S/c1-6-3(4(7)8)2-11-5(9)10/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m0/s1

638-23-3 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (C0863)  S-(Carboxymethyl)-L-cysteine  >98.0%(HPLC)(T) 638-23-3 25g 390.00CNY Detail
Alfa Aesar (B23487)  S-Carboxymethyl-L-cysteine, 97%    638-23-3 25g 466.0CNY Detail
Alfa Aesar (B23487)  S-Carboxymethyl-L-cysteine, 97%    638-23-3 100g 1358.0CNY Detail
Sigma-Aldrich (C0470000)  Carbocisteine  European Pharmacopoeia (EP) Reference Standard 638-23-3 C0470000 1,880.19CNY Detail

638-23-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name S-carboxymethyl-L-cysteine

1.2 Other means of identification

Product number -
Other names S-Carboxymethyl-L-cysteine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:638-23-3 SDS

638-23-3Synthetic route

DL-cysteine hydrochloride
10318-18-0

DL-cysteine hydrochloride

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With Iodoacetic acid100%
L-cysteine hydrochloride

L-cysteine hydrochloride

chloroacetic acid
79-11-8

chloroacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With ammonia; sodium carbonate; sodium sulfite In water at 55℃; for 0.5h; pH=3 - 7.3; pH-value; Concentration; Reagent/catalyst; Temperature;96.7%
l-cysteine hydrochloride
52-89-1

l-cysteine hydrochloride

chloroacetic acid
79-11-8

chloroacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With ammonia; ammonium bicarbonate In water at 20 - 50℃; for 0.5h; pH=7.5; Reagent/catalyst; Temperature; pH-value; Large scale;96%
L-Cysteine
52-90-4

L-Cysteine

Iodoacetic acid
64-69-7

Iodoacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
in schwach alkalischer oder neutraler wss. Loesung;
In water at 20℃; for 0.25h;
L-Cysteine
52-90-4

L-Cysteine

chloroacetic acid
79-11-8

chloroacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
in schwach alkalischer oder neutraler wss. Loesung;
L-cystine
56-89-3

L-cystine

chloroacetic acid
79-11-8

chloroacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With sodium hydroxide; zinc at 30℃;
With sodium amide In ammonia
With ammonia; sodium
sodium monochloroacetic acid
3926-62-3

sodium monochloroacetic acid

2-amino-(2)-thiazoline-4-carboxylic acid
2150-55-2

2-amino-(2)-thiazoline-4-carboxylic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
at 26℃; for 8h; potassium phosphate buffer pH 8.0, Pseudomonas desmolitica AJ 11898;
L-Cysteine
52-90-4

L-Cysteine

mercaptoacetic acid
68-11-1

mercaptoacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With Tris-HCl buffer at 30℃; for 0.166667h; β-cyano-L-alanine synthase (from Spinacia oleracea, Chenopodiaceae);
With Tris-HCl buffer; β-cyano-L-alanine synthase (from Spinacea oleracea, Chenopodiaceae) at 30℃; for 0.166667h;
2-amino-3-chloropropanoic acid
2731-73-9

2-amino-3-chloropropanoic acid

mercaptoacetic acid
68-11-1

mercaptoacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With potassium phosphate; pyridoxal 5'-phosphate In water at 37℃; for 24h; enzyme catalyst: S-carboxymethyl-L-cysteine synthase from Escherichia coli W3110;
O-acetyl-L-serine
5147-00-2

O-acetyl-L-serine

mercaptoacetic acid
68-11-1

mercaptoacetic acid

carbocisteine
638-23-3

carbocisteine

L-Cysteine
52-90-4

L-Cysteine

Iodoacetic acid
64-69-7

Iodoacetic acid

water
7732-18-5

water

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
in neutraler Loesung;
L-Cysteine
52-90-4

L-Cysteine

chloroacetic acid
79-11-8

chloroacetic acid

aqueous KOH

aqueous KOH

carbocisteine
638-23-3

carbocisteine

Iodoacetic acid
64-69-7

Iodoacetic acid

(R)-thiazolidine-carboxylic acid-(4)

(R)-thiazolidine-carboxylic acid-(4)

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With potassium carbonate at 20℃;
L-Cysteine
52-90-4

L-Cysteine

sodium monochloroacetic acid
3926-62-3

sodium monochloroacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With sodium hydroxide In water
L-cystine
56-89-3

L-cystine

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
In sodium hydroxide; water
L-phosphoserine
407-41-0

L-phosphoserine

mercaptoacetic acid
68-11-1

mercaptoacetic acid

carbocisteine
638-23-3

carbocisteine

Conditions
ConditionsYield
With ethylenediaminetetraacetic acid; O-phospho-L-serine sulfhydrylase from Aeropyrum pernix K1 In aq. phosphate buffer; N,N-dimethyl-formamide at 80℃; for 0.05h; pH=7.5; Enzymatic reaction;
carbocisteine
638-23-3

carbocisteine

acetic anhydride
108-24-7

acetic anhydride

N-Acetyl-S-carboxymethyl-L-cysteine
26177-54-8

N-Acetyl-S-carboxymethyl-L-cysteine

Conditions
ConditionsYield
In water at 0℃; pH 7.0;99%
carbocisteine
638-23-3

carbocisteine

S-(carboxymethyl)-L-cysteine monoammonium

S-(carboxymethyl)-L-cysteine monoammonium

Conditions
ConditionsYield
With ammonium hydroxide at 20℃; Temperature;98%
carbocisteine
638-23-3

carbocisteine

L-arginine
74-79-3

L-arginine

S-(carboxymethyl)-L-cysteine arginine

S-(carboxymethyl)-L-cysteine arginine

Conditions
ConditionsYield
In water at 20 - 50℃;95.7%
manganese(II) chloride tetrahydrate

manganese(II) chloride tetrahydrate

carbocisteine
638-23-3

carbocisteine

[manganese(II)(H2O)(S-carboxymethyl-L-cysteine(-2H))]

[manganese(II)(H2O)(S-carboxymethyl-L-cysteine(-2H))]

Conditions
ConditionsYield
With NaOH In water NaOH added to soln. of MnCl2*4H2O (1.0 mmol), ppt. centrifuged, washed (H2O), added to soln. of H2SCMC (1.0 mmol), stirred for 10 min; ppt. filtered off, crystd. at 45°C over 15 d; elem. anal.;76%
carbocisteine
638-23-3

carbocisteine

4-formylphenylboronic acid,
87199-17-5

4-formylphenylboronic acid,

(S,E)-2-((4-boronobenzylidene)amino)-3-(4-hydroxyphenyl)propanoic acid

(S,E)-2-((4-boronobenzylidene)amino)-3-(4-hydroxyphenyl)propanoic acid

Conditions
ConditionsYield
In methanol at 85℃; for 48h;74.67%
carbocisteine
638-23-3

carbocisteine

S-Carboxymethyl-L-cysteine-sulfoxide
5439-87-2

S-Carboxymethyl-L-cysteine-sulfoxide

Conditions
ConditionsYield
With dihydrogen peroxide; sodium hydrogencarbonate at 4℃; for 96h;70%
With dihydrogen peroxide
With perchloric acid; dihydrogen peroxide
carbocisteine
638-23-3

carbocisteine

p-carboxyphenylsulfonyl chloride
10130-89-9

p-carboxyphenylsulfonyl chloride

N-(4-carboxyphenylsulfonyl)-S-carboxymethyl-L-cysteine
1336899-18-3

N-(4-carboxyphenylsulfonyl)-S-carboxymethyl-L-cysteine

Conditions
ConditionsYield
With sodium hydroxide In water at 20℃; for 6h;63%
zinc(II) nitrate
10196-18-6

zinc(II) nitrate

carbocisteine
638-23-3

carbocisteine

water
7732-18-5

water

[Zn(S-carboxymethyl-L-cysteine(-2H))(H2O)](n)

[Zn(S-carboxymethyl-L-cysteine(-2H))(H2O)](n)

Conditions
ConditionsYield
With NaOH In water aq. soln. of L-cysteine derivative added to aq. soln. of Zn salt, pH adjusted to 6.0 by addn. of aq. NaOH, mixt. stirred for 2 h; filtered, crystn. from filtrate after 1 week; elem. anal.;61%
carbocisteine
638-23-3

carbocisteine

S-Carboxymethyl-L-cysteine S,S-Dioxide
25515-73-5

S-Carboxymethyl-L-cysteine S,S-Dioxide

Conditions
ConditionsYield
With dihydrogen peroxide In water at 40℃; for 192h;53%
With Peroxyformic acid
With dihydrogen peroxide
With perchloric acid; dihydrogen peroxide
carbocisteine
638-23-3

carbocisteine

water
7732-18-5

water

cadmium(II) nitrate

cadmium(II) nitrate

([Cd(S-carboxymethyl-L-cysteine(-2H))(H2O)]*2H2O)(n)

([Cd(S-carboxymethyl-L-cysteine(-2H))(H2O)]*2H2O)(n)

Conditions
ConditionsYield
With NaOH In water aq. soln. of L-cysteine derivative added to aq. soln. of Cd salt, pH adjusted to 6.0 by addn. of aq. NaOH, mixt. stirred for 2 h; filtered, crystn. from filtrate after a few days; elem. anal.;51%
phthalic anhydride
85-44-9

phthalic anhydride

carbocisteine
638-23-3

carbocisteine

N-phthaloyl-S-carboxymethyl-cysteine
185342-50-1

N-phthaloyl-S-carboxymethyl-cysteine

Conditions
ConditionsYield
at 180 - 185℃;45%
copper(II) nitrate hexahydrate

copper(II) nitrate hexahydrate

carbocisteine
638-23-3

carbocisteine

[Cu(S-carboxymethyl-L-cysteine(-2H))(H2O)](n)

[Cu(S-carboxymethyl-L-cysteine(-2H))(H2O)](n)

Conditions
ConditionsYield
With NaOH In water aq. soln. of L-cysteine derivative added to aq. soln. of Cu salt, pH adjusted to 6.0 by addn. of aq. NaOH, mixt. stirred for 2 h; filtered, slow crystn. from filtrate within several weeks; elem. anal.;41%
methanol
67-56-1

methanol

carbocisteine
638-23-3

carbocisteine

S-methoxycarbonylmethyl-L-cysteine ; hydrochloride
24815-26-7

S-methoxycarbonylmethyl-L-cysteine ; hydrochloride

Conditions
ConditionsYield
With hydrogenchloride
carbocisteine
638-23-3

carbocisteine

benzoyl chloride
98-88-4

benzoyl chloride

N-benzoyl-S-carboxymethyl-L-cysteine
6332-29-2

N-benzoyl-S-carboxymethyl-L-cysteine

Conditions
ConditionsYield
With sodium hydroxide
With sodium hydroxide
With sodium hydroxide
carbocisteine
638-23-3

carbocisteine

phenyl isothiocyanate
103-72-0

phenyl isothiocyanate

((R)-5-oxo-1-phenyl-2-thioxo-imidazolidin-4-ylmethylsulfanyl)-acetic acid
50997-33-6

((R)-5-oxo-1-phenyl-2-thioxo-imidazolidin-4-ylmethylsulfanyl)-acetic acid

Conditions
ConditionsYield
With pyridine; sodium hydroxide
methanol
67-56-1

methanol

carbocisteine
638-23-3

carbocisteine

S-Methoxycarbonylmethyl-L-cystein-methylester
24815-27-8

S-Methoxycarbonylmethyl-L-cystein-methylester

Conditions
ConditionsYield
With hydrogenchloride
With hydrogenchloride
ethanol
64-17-5

ethanol

carbocisteine
638-23-3

carbocisteine

S-ethoxycarbonylmethyl-L-cysteine ethyl ester
60115-20-0

S-ethoxycarbonylmethyl-L-cysteine ethyl ester

Conditions
ConditionsYield
With hydrogenchloride
carbocisteine
638-23-3

carbocisteine

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

N-Carbethoxy-S-carboxymethyl-L-cysteine

N-Carbethoxy-S-carboxymethyl-L-cysteine

Conditions
ConditionsYield
With sodium hydroxide; sodium acetate
carbocisteine
638-23-3

carbocisteine

benzyl chloroformate
501-53-1

benzyl chloroformate

N-Benzyloxycarbonyl-S-carboxymethyl-L-cystein
47173-61-5

N-Benzyloxycarbonyl-S-carboxymethyl-L-cystein

Conditions
ConditionsYield
With sodium hydroxide
carbocisteine
638-23-3

carbocisteine

phenylacetyl chloride
103-80-0

phenylacetyl chloride

S-Carboxylmethyl-N-phenylacetyl-L-cystein

S-Carboxylmethyl-N-phenylacetyl-L-cystein

Conditions
ConditionsYield
With potassium hydroxide
L-valine
72-18-4

L-valine

L-Cysteine
52-90-4

L-Cysteine

carbocisteine
638-23-3

carbocisteine

(R)-2-{(R)-2-[2-((R)-2-Amino-2-carboxy-ethylsulfanyl)-acetylamino]-3-mercapto-propionylamino}-3-methyl-butyric acid

(R)-2-{(R)-2-[2-((R)-2-Amino-2-carboxy-ethylsulfanyl)-acetylamino]-3-mercapto-propionylamino}-3-methyl-butyric acid

Conditions
ConditionsYield
With 3-(N-morpholino)propanesulfonic acid; potassium hydroxide; ATP; magnesium chloride; Cycloheximide; diothiothreitol at 25℃; ACV synthetase;
carbocisteine
638-23-3

carbocisteine

A

(2R,4S)-S-carboxymethylcysteine sulfoxide
112246-66-9

(2R,4S)-S-carboxymethylcysteine sulfoxide

B

(2R,4R)-S-carboxymethylcysteine sulfoxide
61475-35-2

(2R,4R)-S-carboxymethylcysteine sulfoxide

Conditions
ConditionsYield
With dihydrogen peroxide
With dihydrogen peroxide; sodium hydrogencarbonate at 4℃; for 96h; Yield given. Yields of byproduct given;
With dihydrogen peroxide; sodium hydrogencarbonate In water at 4℃; for 20h; Cooling with ice;
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 638-23-3