103184-06-1Relevant academic research and scientific papers
Synthesis of functionalized pyrazoles and pyrazolopyrimidines as potential leishmanicides
Ram, Vishnu J.,Haque, Navedul
, p. 521 - 524 (2007/10/02)
Various 2-cyano-3-methylthio-3-piperazinylacrylonitriles/acrylamides (2a-k) have been synthesized by the reaction of ketene dithioacetals (1a,b) with substituted piperazines.Reaction of 2a-i with hydrazine hydrate affords the respective pyrazoles (3a-i) w
Synthesis and bactericidal activity of some symmetrical bisthioalkyl derivatives
Seshadri, S.,Sanghavi, N. M.,Naik, R. V.,Tawate, S. R.,Trivedi, M. N.,Fruitwala, M. A.
, p. 688 - 692 (2007/10/02)
The paper deals with the synthesis of some bactericides.The dithioacetal required are obtained by the reaction of active methylene compounds and aryl sulphonamides with carbon disulphide in alkaline conditions and subsequent alkylation with dimethyl sulphate.These compounds are then reacted with various pharmacopohores.All the compounds show moderate to significant activity with few compounds showing very high broad spectrum activity.
