103189-26-0Relevant academic research and scientific papers
In search of open-chain 1,3-stereocontrol
Barbero, Asun,Blakemore, David C.,Fleming, Ian,Wesley, Robert N.
, p. 1329 - 1352 (2007/10/03)
Methylation of methyl 4-phenylpentanoate 25 gives the diastereoisomers methyl (2RS,4SR)-2-methyl-4-phenylpentanoate 26 and methyl (2RS,4RS)- 2-methyl-4-phenylpentanoate 27 in a ratio of 44:56. The aldehydes 3-dimethyl(phenyl)silylbutanal 28, 3-dimethyl(ph
Regio- and Diastereoselective Ene Reactions of Singlet Oxygen with Dialkyl-Substituted Acrylic Esters
Adam, Waldemar,Nestler, Bernd
, p. 1051 - 1053 (2007/10/02)
Photooxygenation of methyl (E)- and (Z)-2-methyl-4-phenyl-2-pentenecarboxylates (E-1, Z-1) afforded the hydroperoxy esters (R*,R*)-2a and (S*,S*)-2b through regiospecific and diastereoselective ene reaction of s
DIASTEREOFACIAL SELECTIVITY VIA ALDOL REACTIONS USING ETHYL DITHIOACETATE AND ETHYL DITHIOPROPIONATE ENOLATES
Meyers, A. I.,Walkup, Robert D.
, p. 5089 - 5106 (2007/10/02)
The lithium enolate of ethyl dithioacetate reacts with α-methyl aldehydes to yield the aldol products in which the syn configuration in the positions β and γ to the thiocarbonyl of the product is favored over the anti configuration.This selectivity is solvent-dependent, and is enhanced at lower temperatures.In most cases, syn:anti product ratios obtained under these conditions varied from 57:43 to >99:1, depending upon the structure of the α-methyl aldehyde.When the lithium enolate of ethyl dithiopropionate was allowed to react with α-methyl aldehydes, only two out of the four possible diastereomers were detected in the product mixtures.
