103194-75-8

Upstream product

• 10209-10-6 diphenylmethyl (6R,7R)-3-methyl-7β-phenoxyacetamidoceph-3-em-4-carboxylate 

Downstream Products

• 103194-80-5 (6R,7R)-3-Methyl-5,5,8-trioxo-7-(2-phenoxy-acetylamino)-5λ⁶-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 103194-76-9 (2R,6R,7R)-2-Hydroxy-3-methyl-5,5,8-trioxo-7-(2-phenoxy-acetylamino)-5λ⁶-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2-carboxylic acid benzhydryl ester 
• 121534-51-8 diphenylmethyl 2-<(2R,3R)-2-acetonylsulphonyl-4-oxo-3-phenoxyacetamidoazetidin-1-yl>glyoxylate 
• 134830-11-8 diphenylmethyl (6R,7R)-2.2-bis(2'-cyanoethyl)-3-methyl-7β-phenoxyacetamidoceph-3-em-4-carboxylate 1,1-dioxide 

Relevant academic research and scientific papers

Exceptional Oxidative Allylic Rearrangements of 4-Alkoxycarbonyl-3-methyl-ceph-3-em 1,1-Dioxides induced by Palladium-Charcoal

Representatives of the title compounds are converted into 4-alkoxycarbonyl-4-hydroxy-3-methylceph-2-em 1,1-dioxides by the action of palladium-charcoal in ethyl acetate; an X-ray analysis of one of the products reveals that the 4-hydroxy function is α-ori

STUDIES RELATED TO PENICILLINS. PART 27. A STRATEGY FOR THE CONVERSION OF 1,1-DIOXIDES OF PENICILLANATES INTO 1,1-DIOXIDES OF 3-METHYLCEPH-3-EM-4-CARBOXYLATES

Methodology for the conversion of benzyl (3S,5R)-penicillinate 1,1-dioxide (2b) into (6R)-4-benzyloxycarbonyl-3-methylceph-3-em 1,1-dioxide (3b) has been devised.In the process, the 3,4-double bond of the product was constructed by a reductive carbonyl-ca