103198-87-4

Basic information

• Product Name: 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-cyclohexyl]-3,3-dimethyl-hexanoic acid methyl ester
• Synonyms: 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-cyclohexyl]-3,3-dimethyl-hexanoic acid methyl ester
• CAS NO: 103198-87-4
• Molecular Weight: 396.611
• Mol File: 103198-87-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-cyclohexyl]-3,3-dimethyl-hexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-cyclohexyl]-3,3-dimethyl-hexanoic acid methyl ester(103198-87-4)
• EPA Substance Registry System: 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-cyclohexyl]-3,3-dimethyl-hexanoic acid methyl ester(103198-87-4)

Safety Data

• Hazardous Substances Data: 103198-87-4(Hazardous Substances Data)

Upstream product

• 103198-82-9 (Z)-6-[4-((Z)-5-Methoxycarbonyl-4,4-dimethyl-pent-1-enyl)-phenyl]-3,3-dimethyl-hex-5-enoic acid methyl ester 
• 77514-26-2 3,3-dimethyl-5-oxopentanoic acid methyl ester 
• 1519-47-7 [p-phenylenebis(methylene)]bis[triphenylphosphonium] dichloride 
• 103198-84-1 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-phenyl]-3,3-dimethyl-hexanoic acid methyl ester 

Relevant articles and documents

Synthesis and Hypolipidemic and Antidiabetogenic Activities of β,β,β',β'-Tetrasubstituted, Long-Chain Dioic Acids

β,β,β',β'-Tetrasubstituted, long-chain dioic acids of the general formula HOOC-C(XY)-C(R2)-Q-C(XY)-COOH have been synthesized and evaluated as hypotriglyceridemic-hypocholesterolemic agents in rats and as antidiabetogenic agents in ob/ob diabetic mice.The free carboxyl function of analogues of the series was mandatory for their hypolipidemic-antidiabetogenic effect while nonhydrolyzable diesters were inactive.Other structure-activity relationships were determined as a function of the overall chain length (C12-C22), α,α'-substitutions (X,Y=H,F,Cl,Br,OH,CN), β,β'-substitutions (R=CH3,C6H5), and core substitutions 2, 1,4-C6H42, 1,4-C6H4(CH=CHCH2)2, CH2(OCH2CH2)3OCH2)>.The most effective hypolipidemic-antidiabetogenic members of the series were α,α'-nonsubstituted, β,β'-methyl-substituted analogues of 14-18-carbon chains having either a saturated aliphatic core or a 1,4-bis(propenyl)benzene core in the cis/trans configuration.The hypotriglyceridemic rather than the hypocholesterolemic capacity of members of the series was found to correlate with their respective capacities as liver peroxisomal proliferation in rats.