77514-26-2

Usage

InChI:InChI=1/C8H14O3/c1-8(2,4-5-9)6-7(10)11-3/h5H,4,6H2,1-3H3

Upstream product

• 3375-31-3 palladium diacetate 
• 63721-05-1 methyl 3,3-dimethyl-4-penteneoate 
• 98560-83-9 methyl 3,3-dimethyl-5-hydroxypentanoate 
• 694-59-7 pyridine N-oxide 
• 180304-63-6 5-bromo-3,3-dimethylpentanoic acid-methyl ester 
• 77514-25-1 methyl 3,3-dimethyl-5-phenylthiopentanoate 
• 27151-66-2 2,2-dimethyl-propane-1,3-dicarboxylic acid monomethyl ester 

Downstream Products

• 103198-82-9 (Z)-6-[4-((Z)-5-Methoxycarbonyl-4,4-dimethyl-pent-1-enyl)-phenyl]-3,3-dimethyl-hex-5-enoic acid methyl ester 
• 144681-98-1 methyl 8-benzyloxy-3,3-dimethyl-5-octenoate 
• 144682-05-3 methyl 3,3-dimethyl-8-(p-toluenesulfonyloxy)octanoate 
• 144681-99-2 methyl 8-benzyloxy-3,3-dimethyloctanoate 
• 333-33-5 8-fluoro-3,3-dimethyloctanoic acid 
• 103198-84-1 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-phenyl]-3,3-dimethyl-hexanoic acid methyl ester 
• 103198-87-4 6-[4-(5-Methoxycarbonyl-4,4-dimethyl-pentyl)-cyclohexyl]-3,3-dimethyl-hexanoic acid methyl ester 

Relevant academic research and scientific papers

Halogenated esters useful as intermediates for insecticides

The invention provides novel compounds of formula: where X represents chloro or bromo and R represents hydrogen or alkyl of up to 4 carbon atoms, processes for preparing them and their use as intermediates in the preparation of insecticidal cyclopropane derivatives. Also provided are novel compounds of formula: wherein R represents alkyl of up to 4 carbon atoms, useful as intermediates in the preparation of the compounds of formula I.

Synthesis of ω-fluorinated octanoic acid and its β-substituted derivatives

Simple syntheses are described for the ω-fluorinated analogs of octanoic acid and its β-substituted derivatives in which insertion of a methyl and dimethyl group, and oxygen substitution at the C-3 position are involved, employing nucleophilic displacement with fluoride ion of the tosylate functions in the later stage of synthesis.The synthetic procedures offer easy and convenient acces to the corresponding 18F-labeled analogs using the readily available fluoride ion.

FACILE SYNTHESIS OF 3,4-DIHYDRO-4,4-DIMETHYL-2H-PYRAN-2-ONE VIA PALLADIUM CATALYZED TERMINAL OXIDATION OF 3,3-DIMETHYL-4-PENTENOATES

Selective terminal oxidation of 3,3-dimethyl-4-pentenoates does occur under chloride-free Wacker conditions in AcOH to give 5-acetoxy-3,3-dimethyl-4-pentenoates (7) and their analogues (2,8) in good yields.Successive cyclization of 7 and 8 at vapor phase pyrolysis on SiO2 affords 3,4-dihydro-4,4-dimethyl-2H-pyran-2-one (1).

Derivatives of 2H-pyran-2-one

Processes for producing a (1α, 4α, 5α)-6,6-dimethyl-4-halo-substituted-methyl-3-oxabicyclo[3.1.0]hexan-2-one and its novel intermediates from known and inexpensive starting materials are described and exemplified.