103204-28-0

Usage

Uses

Used in Pharmaceutical Applications:
β-hydroxy-2-methoxy-benzenepropanenitrile is used as a potential drug candidate for its anti-inflammatory and antioxidant properties. It is being studied for its potential to alleviate inflammation and oxidative stress, which are common in various diseases and conditions.
Used in Neuroprotection:
β-hydroxy-2-methoxy-benzenepropanenitrile is used as a neuroprotective agent, which may help protect the nervous system from damage or degeneration. This could be particularly beneficial in the treatment of neurodegenerative diseases such as Alzheimer's, Parkinson's, and multiple sclerosis.
Used in Plant Defense:
In the context of plants, β-hydroxy-2-methoxy-benzenepropanenitrile is used as a natural defense compound against pests or pathogens. It may contribute to the plant's overall resistance and survival in the face of various environmental challenges.
Used in Industrial Applications:
β-hydroxy-2-methoxy-benzenepropanenitrile may also have potential uses in various industrial applications, such as in the development of new materials or processes that can benefit from its unique chemical properties. Further research and development in this area could lead to innovative uses for β-hydroxy-2-methoxy-benzenepropanenitrile.

Upstream product

• 135-02-4 ortho-anisaldehyde 
• 590-17-0 cyanomethyl bromide 
• 18293-53-3 2-trimethylsilylacetonitrile 
• 75-05-8 acetonitrile 
• 31949-21-0 bromomethyl 2-methoxyphenyl ketone 

Downstream Products

• 103095-62-1 3-hydroxy-3-(2-methoxy-phenyl)-propionic acid amide 

Relevant academic research and scientific papers

Unexpected stereorecognition in nitrilase-catalyzed hydrolysis of β-hydroxy nitriles

Biocatalytic enantioselective hydrolysis of β-hydroxy nitriles to corresponding (S)-enriched β-hydroxy carboxylic acids has been achieved for the first time by an isolated nitrilase bII6402 from Bradyrhizobium japonicum USDA110. This offers a new "green" approach to optically pure β-hydroxy nitriles and β-hydroxy carboxylic acids. The observed remote stereorecognition is surprising because this nitrilase shows no enantioselectivity for the hydrolysis of α-hydroxy nitriles such as mandelonitrile.

One-pot nitrile aldolization/hydration operation giving β-hydroxy carboxamides

Rhodium to the rescue: The formal aldol products of carboxamides (CONH 2) were obtained by using a RhI(OR) (R=H, Me) catalyst under essentially neutral pH and ambient conditions. This novel aldol strategy is based on the catalytic al

P(i-PrNCH2CH2)3N as a Lewis base catalyst for the synthesis of β-hydroxynitriles using TMSAN

(Equation Presented) Proazaphosphatrane 1a was found to be an efficient catalyst for synthesis of β-hydroxynitriles via the reaction of trimethylsilylacetonitrile (TMSAN) with aldehydes under mild reaction conditions and typically low catalyst loading (ca. 2 mol %). A variety of functional groups were tolerated, and good to excellent product yields were obtained.

RhI-catalyzed aldol-type reaction of organonitriles under mild conditions

An aldol-type reaction of organonitriles with aldehydes was catalyzed by a RhI(OR) species under ambient conditions, and the reaction displayed a broad substrate scope with respect to both organonitrile and aldehyde components. The Royal Societ