103205-33-0 Usage
Uses
Used in Pharmaceutical Industry:
3'-Acetylamino-2'-hydroxyacetophenone is used as a key intermediate in the synthesis of antitumor agents, specifically for the development of breast cancer treatments. Its unique molecular structure allows it to be incorporated into the design of novel therapeutic agents that can target and combat cancer cells more effectively.
In the preparation of Antitumor Agents in Breast Cancer:
3'-Acetylamino-2'-hydroxyacetophenone plays a crucial role in the development of antitumor agents for breast cancer treatment. Its incorporation into the molecular structure of these agents enables the design of drugs that can specifically target and inhibit the growth and proliferation of breast cancer cells. This contributes to the advancement of more effective and targeted cancer therapies, ultimately improving patient outcomes and survival rates.
Check Digit Verification of cas no
The CAS Registry Mumber 103205-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,2,0 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 103205-33:
(8*1)+(7*0)+(6*3)+(5*2)+(4*0)+(3*5)+(2*3)+(1*3)=60
60 % 10 = 0
So 103205-33-0 is a valid CAS Registry Number.
103205-33-0Relevant articles and documents
Method for preparing N-(3-acetyl-2-hydroxyphenyl)acetamide
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Paragraph 0036; 0046-0048; 0049; 0059-0064, (2019/07/04)
The invention relates to the technical field of organic synthesis and medicine, and provides a method for preparing N-(3-acetyl-2-hydroxyphenyl)acetamide. According to the method, 2-aminophenol is adopted as an initial raw material, amidogen acetylation and a methylation reaction of phenolic hydroxyl groups are firstly carried out, then bromination on benzene rings is carried out, acetyl is introduced, reductive debromination is finally carried out, a target product is obtained, and the total yield reaches up to 41.7%. In the process of generating a compound E through a compound D, the compound D is subjected to ether bond cracking, and can react with acetylchloride to generate phenolic ester, and then a rearrangement reaction occurs. According to the method, the raw material is wide in source and easy to obtain, the path can be industrialized easily, fewer impurities are generated, the yield is high, and the purity of the target product is effectively improved.
