1032153-48-2Relevant academic research and scientific papers
PREPARATION METHOD OF 2-DEOXY-L-RIBOSE
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Page/Page column 4, (2009/12/05)
A method of preparing 2-deoxy-L-ribose represented by the following formula I is disclosed. The preparation method includes the steps of: treating L-arabinose with an alcohol solvent in the presence of an acid to prepare 1-alkoxy-L-arabinopyranose; allowi
THE PREPARATION METHOD OF 2-DE0XY-L-RIB0SE
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Page/Page column title page; 14-15, (2008/12/06)
A method of preparing 2-deoxy-L-ribose represented by the following formula I is disclosed. The preparation method includes the steps of : treating L-arabinose with an alcohol solvent in the presence of an acid to prepare 1-alkoxy-L- arabinopyranose; allowing the prepared 1-alkoxy-L- arabinopyranose to react with acyl chloride so as to prepare l-alkoxy-2, 3, 4-triacyl-L-arabinopyranose; brominating the alkoxy group of the prepared l-alkoxy-2, 3, 4-triacyl-L- arabinopyranose to prepare a l-bromo-2, 3, 4-triacyl compound; allowing the prepared compound to react with zinc in the presence of ethyl acetate and an organic base so as to prepare glycal; treating the glycal with an alcohol solvent in the presence of an acid to prepare l-alkoxy-2-deoxy-3, 4- diacyl-L-ribopyranose; treating the prepared l-alkoxy-2- deoxy-3, 4-diacyl-L-ribopyranose with a base to prepare 1- alkoxy-2-deoxy-L-ribopyranose; and hydrolyzing the prepared l-alkoxy-2-deoxy-L-ribopyranose in the presence of an acid catalyst.
