1032324-37-0

Basic information

• Product Name: [1-((4-chloro-2-fluorobenzene)sulfonyl)piperidin-4-yl]diphenylmethanol
• Synonyms: [1-((4-chloro-2-fluorobenzene)sulfonyl)piperidin-4-yl]diphenylmethanol
• CAS NO: 1032324-37-0
• Molecular Weight: 459.969
• Mol File: 1032324-37-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1-((4-chloro-2-fluorobenzene)sulfonyl)piperidin-4-yl]diphenylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: [1-((4-chloro-2-fluorobenzene)sulfonyl)piperidin-4-yl]diphenylmethanol(1032324-37-0)
• EPA Substance Registry System: [1-((4-chloro-2-fluorobenzene)sulfonyl)piperidin-4-yl]diphenylmethanol(1032324-37-0)

Safety Data

• Hazardous Substances Data: 1032324-37-0(Hazardous Substances Data)

Upstream product

• 141337-26-0 4-chloro-2-fluorobenzenesulfonyl chloride 
• 115-46-8 C₁₈H₂₁NO 
• 100-58-3 phenylmagnesium bromide 
• 14548-46-0 4-Benzoylpyridine 
• 20735-04-0 (1,2,3,6-tetrahydro-1-methylpyridin-4-yl)diphenylmethanol 
• 6071-92-7 VUF 4589 
• 1620-30-0 diphenyl(pyridin-4-yl)methanol 
• 112818-77-6 ethyl 4-(hydroxydiphenylmethyl)piperidine-1-carboxylate 

Relevant articles and documents

Synthesis and in vitro antiproliferative activity of diphenyl(sulphonylpiperidin-4-yl)methanol derivatives

A series of novel diphenyl(piperidin-4-yl)methanol derivatives 10(a-n) were synthesized and characterized by 1H NMR, LC/MS, FTIR, and elemental analyses. All the synthesized compounds were evaluated for cell proliferation by MTT assay. The antiproliferative effects of the synthesized compounds were tested against viable human skin fibroblast cell line and carcinoma cell lines, namely HeLa cells, HT-29 cells, MCF-7 cells, and HepG-2 cells in comparing the positive and negative control. Among the synthesized compounds, (10b) and (10g) have been identified as potent antiproliferative agents.