103237-52-1 Usage
Uses
Used in Pharmaceutical Industry:
Oxociprofloxacin is used as an active pharmaceutical ingredient for its antibacterial properties. It is particularly effective against a wide range of bacterial infections due to its ability to interfere with bacterial DNA replication, leading to the inhibition of bacterial growth and ultimately the eradication of the infection.
Used in Research and Development:
In the field of research and development, oxociprofloxacin serves as a valuable compound for studying the mechanisms of action of fluorinated quinolone antibacterials. Its chemical properties and metabolite status make it an important subject for understanding the development of resistance and the design of new, more effective antibacterial agents.
Used in Drug Delivery Systems:
Similar to gallotannin, oxociprofloxacin can also be incorporated into drug delivery systems to enhance its bioavailability, targeting, and therapeutic outcomes. These systems may include nanoparticles, liposomes, or other advanced formulations that aim to improve the drug's pharmacokinetics and reduce potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 103237-52-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,2,3 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 103237-52:
(8*1)+(7*0)+(6*3)+(5*2)+(4*3)+(3*7)+(2*5)+(1*2)=81
81 % 10 = 1
So 103237-52-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H16FN3O4/c18-12-5-10-13(6-14(12)20-4-3-19-15(22)8-20)21(9-1-2-9)7-11(16(10)23)17(24)25/h5-7,9H,1-4,8H2,(H,19,22)(H,24,25)
103237-52-1Relevant academic research and scientific papers
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-oxo-1-piperazinyl)-3-quinolinecarboxylic acid antibacterial agents
-
, (2008/06/13)
Novel antibacterially active 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(3-oxo-1-piperazinyl)-3-quinolinecarboxylic acids of the formula STR1 in which R1 is hydrogen, methyl or ethyl, and R2 is hydrogen or fluorine, and pharmaceutically tolerable hydrates and salts thereof.
Isolation and structural elucidation of urinary metabolites of ciprofloxacin
Gau,Kurz,Petersen,Ploschke,Wuensche
, p. 1545 - 1549 (2007/10/02)
After oral administration of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-1-ylqu inoline-3-carboxylic acid (ciprofloxacin, Bay o 9867; designated trademark: Ciprobay) four metabolites M1-M4 were isolated from human urine by Craig counter current distribution and semipreparative high-performance liquid chromatography. Their molecular structures were elucidated by nuclear magnetic resonance and mass spectrometry and confirmed by comparing their spectra with those of authentic synthetic reference compounds.
