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86393-33-1

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  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Manufacturer/High quality/Best price/In stock

    Cas No: 86393-33-1

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  • Dayang Chem (Hangzhou) Co.,Ltd.
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  • High quality 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-Oxoquinoline-3-Carboxylic Acid supplier in China

    Cas No: 86393-33-1

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  • Simagchem Corporation
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  • High quality 7-Chloro-6-fluoro-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acid with best price cas:86393-33-1

    Cas No: 86393-33-1

  • USD $ 250.0-350.0 / Kilogram

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86393-33-1 Usage

Chemical Properties

Off-White Crystalline Powder

Uses

Different sources of media describe the Uses of 86393-33-1 differently. You can refer to the following data:
1. An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial
2. A metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.
3. 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.

General Description

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.

Check Digit Verification of cas no

The CAS Registry Mumber 86393-33-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,3,9 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 86393-33:
(7*8)+(6*6)+(5*3)+(4*9)+(3*3)+(2*3)+(1*3)=161
161 % 10 = 1
So 86393-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H9ClFNO3/c14-9-4-11-7(3-10(9)15)12(17)8(13(18)19)5-16(11)6-1-2-6/h3-6H,1-2H2,(H,18,19)/p-1

86393-33-1 Well-known Company Product Price

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  • TCI America

  • (C2293)  7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid  >98.0%(HPLC)(T)

  • 86393-33-1

  • 5g

  • 290.00CNY

  • Detail
  • TCI America

  • (C2293)  7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid  >98.0%(HPLC)(T)

  • 86393-33-1

  • 25g

  • 750.00CNY

  • Detail
  • Sigma-Aldrich

  • (PHR1174)  Fluoroquinolonicacid  pharmaceutical secondary standard; traceable to USP

  • 86393-33-1

  • PHR1174-500MG

  • 952.15CNY

  • Detail
  • Sigma-Aldrich

  • (C2190050)  CiprofloxacinimpurityA  European Pharmacopoeia (EP) Reference Standard

  • 86393-33-1

  • C2190050

  • 1,880.19CNY

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  • USP

  • (1278302)  Fluoroquinolonicacid  United States Pharmacopeia (USP) Reference Standard

  • 86393-33-1

  • 1278302-150MG

  • 14,578.20CNY

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  • Aldrich

  • (531901)  7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylicacid  96%

  • 86393-33-1

  • 531901-25G

  • 2,544.75CNY

  • Detail

86393-33-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid

1.2 Other means of identification

Product number -
Other names 7-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86393-33-1 SDS

86393-33-1Relevant articles and documents

An operational transformation of 3-carboxy-4-quinolones into 3-nitro-4-quinolones via ipso-nitration using polysaccharide supported copper nanoparticles: Synthesis of 3-tetrazolyl bioisosteres of 3-carboxy-4-quinolones as antibacterial agents

Azad, Chandra S.,Narula, Anudeep K.

, p. 19052 - 19059 (2016/03/01)

Chitosan supported Cu nano-particles have been synthesized, and utilized for the synthesis of 3-nitro-4-quinolones from 3-carboxy-4-quinolones via ipso nitration. The synthesized 3-nitro derivatives of 4-quinolones were successfully converted into their 3-tetrazolyl bioisosteres which showed increased antibacterial activity as compared to the standard ciprofloxacin.

Synthesis, characterization and biological studies of some homodinuclear complexes of zinc with second-generation quinolone drug and neutral bidentate ligands

Patel,Chhasatia,Dosi,Bariya,Thakkar

scheme or table, p. 1918 - 1924 (2010/08/21)

The novel homodinuclear zinc(II) complexes with the quinolone antibacterial drugs ciprofloxacine and neutral bidentate ligands have been synthesized and characterized by elemental analysis, TG analyses and various spectroscopic techniques. The metal ion exhibits octahedral geometry with two water molecule in the inner sphere cavity environment. The interaction of complexes with DNA was determined using absorption titration, viscosity measurements and electrophoresis technique. The intrinsic binding constants (Kb) of complexes were determined, which were ranging from 1.0 × 104 to 3.5 × 104 per mole. Suggesting that complexes bind more strongly to DNA. Effect on viscosity has also been checked to authenticate the binding of metal complexes with DNA. An antimicrobial activity of all the ligands and metal complexes has been examined by minimum inhibitory concentration method (MIC).

Compounds with antibacterial and antiparasitic properties

-

, (2008/06/13)

There are provided novel compounds which have both antibacterial and antiparasitic properties, thereby reducing the need for using several compounds in combined antibacterial and antiparasitic treatment of livestock. The present novel compounds are especially well suited for treatment of coccidiosis, and they are represented by general formula (I) wherein R1-R6, X and A are as defined in the specification.

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