103238-71-7Relevant articles and documents
Synthetic studies on L-proline and (4R)-hydroxy-L-proline derivatives
González, Teresa,Abad, Olga,Santano, M. Carmen,Minguillón, Cristina
, p. 1171 - 1182 (2007/10/03)
The preparation of a number of L-proline and (4R)-hydroxy-L-proline derivatives to assess their enantioselectivity when applied to several techniques and experimental conditions is described. All the derivatives prepared incorporated at least one 3,5-disubstituted aromatic ring that contained nitro, chloro or methyl groups and were obtained by classical methods. In spite of the difficulties that arise from the presence of rotational isomers in most cases, the compounds studied are fully described by their 1H and 13C NMR spectra.