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1032392-72-5

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1032392-72-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1032392-72-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,2,3,9 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1032392-72:
(9*1)+(8*0)+(7*3)+(6*2)+(5*3)+(4*9)+(3*2)+(2*7)+(1*2)=115
115 % 10 = 5
So 1032392-72-5 is a valid CAS Registry Number.

1032392-72-5Relevant articles and documents

OXIME-CONTAINING MACROCYCLIC ACYL GUANIDINES AS BETA-SECRETASE INHIBITORS

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Page/Page column 10-11, (2008/12/06)

There is provided a series of oxime-containing macrocyclic acyl guanidines of Formula (I) or a stereoisomer; or a pharmaceutically acceptable salt thereofwherein R1, R2, R3, R4, n and X as defined herein, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor protein (APP) by β-secretase and, more specifically, inhibit the production of Aβ-peptide. The present disclosure is directed to compounds useful in the treatment of neurological disorders related to β-amyloid production, such as Alzheimer's disease and other conditions affected by anti-amyloid activity.

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