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10324-43-3

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10324-43-3 Usage

Building block in pharmaceuticals and fragrances

The compound serves as a building block in the production of pharmaceuticals and fragrances, contributing to the development of various medications and scented products.

Solvent in chemical processes

The compound can serve as a solvent in various chemical processes, aiding in the dissolution and reaction of other substances.

Check Digit Verification of cas no

The CAS Registry Mumber 10324-43-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,2 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10324-43:
(7*1)+(6*0)+(5*3)+(4*2)+(3*4)+(2*4)+(1*3)=53
53 % 10 = 3
So 10324-43-3 is a valid CAS Registry Number.

10324-43-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-<(4-methoxyphenyl)methyl>benzyl alcohol

1.2 Other means of identification

Product number -
Other names 2-(4-Methoxybenzyl)-benzylalkohol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10324-43-3 SDS

10324-43-3Relevant articles and documents

Palladium-promoted arylation of functionalised organolithium compounds via their zinc derivatives

Yus, Miguel,Gomis, Joaquin

, p. 1989 - 1995 (2002)

The reaction of different functionalised organolithium compounds 2, 5, 8, and 13 [easily prepared by DTBB-catalysed lithiation of isochromane (1), phthalane (4), 2,3-dihydrobenzofuran (7) and 1-chloro-3,3-diethoxypropane (12), respectively] with an equimo

Tricyclic alkylamides as melatonin receptor ligands with antagonist or inverse agonist activity

Lucini, Valeria,Pannacci, Marilou,Scaglione, Francesco,Fraschini, Franco,Rivara, Sivia,Mor, Marco,Bordi, Fabrizio,Plazzi, Pier Vincenzo,Spadoni, Gilberto,Bedini, Annalida,Piersanti, Giovanni,Diamantini, Giuseppe,Tarzia, Giorgio

, p. 4202 - 4212 (2007/10/03)

This work reports the design and synthesis of novel alkylamides, characterized by a dibenzo[a,d] cycloheptene nucleus, as melatonin (MLT) receptor ligands. The tricyclic scaffold was chosen on the basis of previous quantitative structure-activity studies on MT1 and MT2 antagonists, relating selective MT2 antagonism to the presence of an aromatic substituent out of the plane of the MLT indole ring. Some dibenzo seven-membered structures were thus selected because of the noncoplanar arrangement of their benzene rings, and an alkylamide chain was introduced to fit the requirements for MLT receptor binding, namely, dibenzocycloheptenes with an acylaminoalkyl side chain at position 10 and dibenzoazepines with this side chain originating from the nitrogen atom bridging the two phenyl rings. Binding affinity at human cloned MT1 and MT2 receptors was measured by 2[125I] iodomelatonin displacement assay and intrinsic activity by the GTPγS test. The majority of the compounds were characterized by higher affinity at the MT2 than at the MT 1 receptor and by very low intrinsic activity values, thus confirming the importance of the noncoplanar arrangement of the two aromatic rings for selective MT2 antagonism. Dibenzocycloheptenes generally displayed higher MT1 and MT2 affinity than dibenzoazepines. N-(8-Methoxy-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ylmethyl)propionamide (4c) and -butyramide (4d) were the most selective MT2 receptor antagonists of the series, with MT2 receptor affinity comparable to that of melatonin and as such among the highest reported in the literature for MLT receptor antagonists. The acetamide derivative 4b produced a noticeable reduction of GTPγS binding at MT2 receptor, thus being among the few inverse agonists described.

Research in the field of drugs with psychotropic activity. 11-piperazino 10,11-dihydro (a,d)dibenzo cycloheptene derivatives

Fouche,Blondel,Horclois,James,Leger,Poiget

, p. 3113 - 3130 (2007/10/05)

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