10325-65-2

Basic information

• Product Name: 2,3-dibromo-1-(4-methylphenyl)-3-phenylpropan-1-one
• CAS NO: 10325-65-2
• Molecular Formula: C₁₆H₁₄Br₂O
• Molecular Weight: 382.0898
• Mol File: 10325-65-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 430.7°C at 760 mmHg
• Flash Point: 103°C
• Density: 1.579g/cm³
• Vapor Pressure: 1.27E-07mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: 2,3-dibromo-1-(4-methylphenyl)-3-phenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibromo-1-(4-methylphenyl)-3-phenylpropan-1-one(10325-65-2)
• EPA Substance Registry System: 2,3-dibromo-1-(4-methylphenyl)-3-phenylpropan-1-one(10325-65-2)

Safety Data

• Hazardous Substances Data: 10325-65-2(Hazardous Substances Data)

Usage

General Description

2,3-dibromo-1-(4-methylphenyl)-3-phenylpropan-1-one is a chemical compound with the molecular formula C15H12Br2O. It is a yellow crystalline solid, commonly known as dibromoketone. 2,3-dibromo-1-(4-methylphenyl)-3-phenylpropan-1-one is used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. It is also used as a reactant in the formation of other complex organic molecules. The presence of bromine atoms in the compound gives it unique reactivity and makes it useful in a wide range of chemical reactions. Additionally, it has potential applications in the field of medicinal chemistry for the development of new drugs.

Upstream product

• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 
• 100-52-7 benzaldehyde 
• 122-00-9 para-methylacetophenone 
• 30925-52-1 (2Z)-3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one 
• 14802-30-3 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-one 
• 50603-93-5 α-bromo-4'-methyl-chalcone 

Downstream Products

• 32045-93-5 2,3-dimorpholino-3-phenyl-1-(p-tolyl)propan-1-one 
• 6372-29-8 cis-1-cyclohexyl-2-phenyl-3-(p-toluyl)aziridine 
• 6372-29-8 trans-1-cyclohexyl-2-phenyl-3-(p-toluyl)aziridine 
• 50603-93-5 α-bromo-4'-methyl-chalcone 
• 23829-33-6 (1-methyl-3t-phenyl-aziridin-2r-yl)-p-tolyl ketone 
• 6372-58-3 (1-benzyl-3-phenylaziridin-2-yl)(p-tolyl)methanone 
• 6372-58-3 (1-benzyl-3-phenylaziridin-2-yl)(p-tolyl)methanone 
• 29329-38-2 5-phenyl-3-(p-tolyl)isoxazole 
• 25855-99-6 1-(4-methylphenyl)-3-phenyl-1,3-propanedione 
• 141855-26-7 2-(diethylamino)-3-phenyl-1-(p-tolyl)prop-2-en-1-one 
• 74989-99-4 (4R,5R)-4-Bromo-1,5-diphenyl-3-p-tolyl-4,5-dihydro-1H-pyrazole 
• 87275-53-4 5-(Bromo-phenyl-methyl)-4-p-tolyl-1,5-dihydro-imidazol-2-one 
• 87275-48-7 5-Bromo-6-phenyl-4-p-tolyl-5,6-dihydro-1H-pyrimidin-2-one 
• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 

Relevant articles and documents

Modular access to 1,2-allenyl ketones based on a photoredox-catalysed radical-polar crossover process

Herein, a new protocol dealing with the preparation of 1,2-allenyl ketones has been successfully developedviathe reactions of enynes with radicals enabled by dual photoredox/copper catalysis. Based on the results of a deuteration experiment and the competition reaction between cyclopropanation and allenation, the mechanism based on a photoredox-neutral-catalysed radical-polar crossover process has been proposed. Synthetic applications of allenes have also been demonstrated.

GAS-SOLID REACTIONS : PART VI. INTERACTION OF SOLID CHALCONES WITH BROMINE AND IODINE VAPOURS

Solid chalcones (azylidene acetophenones) give, on exposure to bromine vapour at room temperature, the "trans-adduct" in quantitative or near-quantitative yield.Polymorphic forms of several compounds do not differ in their bromination products.Iodine vapours do not cause cis-trans isomerisation in the solid cis-chalcones.