103262-85-7

Upstream product

• 824-46-4 methoxyhydroquinone 
• 75514-03-3 2-methoxy-p-hydroquinone diacetate 

Downstream Products

• 280136-82-5 [3,4-bis-methoxymethoxy-2-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-[2-methoxy-3-methoxymethoxy-6-(3-methyl-but-2-enyloxy)-phenyl]-methanone 
• 280136-77-8 2-methoxy-1-methoxymethoxy-4-(3-methyl-but-2-enyloxy)-benzene 
• 280136-85-8 2-methoxy-4-(3-methyl-but-2-enyloxy)-phenol 
• 280136-84-7 acetic acid 2-methoxy-4-(3-methyl-but-2-enyloxy)-phenyl ester 
• 27257-07-4 2,4-dimethoxyphenyl acetate 

Relevant academic research and scientific papers

Utilization of the inherent nucleophile for regioselective O-acylation of polyphenols via an intermolecular cooperative transesterification

A green and efficient method for regioselective O-acylation of polyphenols has been developed. The acylation can be carried out in potassium carbonate/dimethyl sulphoxide system by utilizing the ‘inherent nucleophile’ via an intermolecular cooperative transesterification under mild condition. This method shows particular advantage in regioselective acylation of polyphenols bearing 2′,4′-dihydroxyacetophenone moiety and can be extended to the synthesis of mono or multiple acetates of polyphenols without this moiety in good yields. Compared with other reported approaches, this method is endowed with atom economy and is more environment-friendly for avoiding the use of any metal-based catalysts.

First synthesis of subelliptenone F, an inhibitor of topoisomerase II

Subelliptenone F, a potent inhibitor of topoisomerase II, was synthesized for the first time via coupling of A and C ring components and B ring formation, followed by Claisen rearrangement of the 3-methyl-2-butenyl ether.