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(2R,4S)-4-Phenylpyrrolidine-2-carboxylic acid, also known as PPCA, is a chiral amino acid derivative with a molecular formula C11H13NO2. It features a pyrrolidine ring with a carboxylic acid group and a phenyl group attached to the fourth position of the ring. PPCA is commonly used in the synthesis of pharmaceuticals and other organic compounds, and has been studied for its potential medicinal properties, including anticonvulsant and antinociceptive effects.

103290-41-1

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103290-41-1 Usage

Uses

Used in Pharmaceutical Synthesis:
PPCA is used as a key intermediate in the synthesis of various pharmaceuticals due to its unique structure and chiral properties. Its presence in the synthesis process can influence the biological activity and selectivity of the resulting compounds.
Used in Organic Chemistry:
As a chiral auxiliary, PPCA is utilized in asymmetric synthesis to help control the stereochemistry of chemical reactions, leading to the production of enantiomerically pure compounds. This is particularly important in the development of drugs, where the desired biological activity is often associated with a specific enantiomer.
Used in Medicinal Research:
PPCA has been studied for its potential medicinal properties, such as anticonvulsant and antinociceptive effects. These properties make it a candidate for the development of new treatments for neurological disorders and pain management.
Used in Chemical Compound Preparation:
PPCA serves as a building block for the preparation of various chemical compounds, including those with potential applications in materials science, agrochemicals, and other specialized fields. Its versatility and unique structural features make it a valuable component in the design and synthesis of novel molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 103290-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,2,9 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 103290-41:
(8*1)+(7*0)+(6*3)+(5*2)+(4*9)+(3*0)+(2*4)+(1*1)=81
81 % 10 = 1
So 103290-41-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h1-5,9-10,12H,6-7H2,(H,13,14)/t9-,10+/m0/s1

103290-41-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (trans)-4-Phenyl-S-proline

1.2 Other means of identification

Product number -
Other names (2R,4R)-4-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103290-41-1 SDS

103290-41-1Downstream Products

103290-41-1Relevant academic research and scientific papers

LITHIUM DIPHENYLCUPRATE REACTIONS WITH 4-TOSYLOXY-L-PROLINES; AN INTERESTING STEREOCHEMICAL OUTCOME. A SYNTHESIS OF TRANS-4-PHENYL-L-PROLINE.

Thottathil, John K.,Moniot, Jerome L.

, p. 151 - 154 (2007/10/02)

The reaction of lithium diphenylcuprate with trans-4- and cis-4-tosyloxy-L-prolines gives excellent yields of 4-phenyl substituted L-prolines and the reaction proceeds with net retention of configuration at the carbon center bearing the tosyloxy group.

Method for making substituted prolines

-

, (2008/06/13)

A method is provided for making substituted prolines of the structure STR1 wherein X is lower alkyl or aryl, R is H, lower alkyl or an alkali metal and Z is an N-protecting group, which method includes the step of reacting a compound of the structure STR2

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