103290-41-1 Usage
General Description
(2R,4S)-4-Phenylpyrrolidine-2-carboxylic acid, also known as PPCA, is a chemical compound with a molecular formula C11H13NO2. It is a chiral amino acid derivative that is commonly used in the synthesis of pharmaceuticals and other organic compounds. It is characterized by a pyrrolidine ring with a carboxylic acid moiety and a phenyl group attached to the fourth position of the ring. PPCA has been studied for its potential medicinal properties, including anticonvulsant and antinociceptive effects. It is also used as a chiral auxiliary in asymmetric synthesis and as a building block for the preparation of various chemical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 103290-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,2,9 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 103290-41:
(8*1)+(7*0)+(6*3)+(5*2)+(4*9)+(3*0)+(2*4)+(1*1)=81
81 % 10 = 1
So 103290-41-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h1-5,9-10,12H,6-7H2,(H,13,14)/t9-,10+/m0/s1
103290-41-1Relevant articles and documents
LITHIUM DIPHENYLCUPRATE REACTIONS WITH 4-TOSYLOXY-L-PROLINES; AN INTERESTING STEREOCHEMICAL OUTCOME. A SYNTHESIS OF TRANS-4-PHENYL-L-PROLINE.
Thottathil, John K.,Moniot, Jerome L.
, p. 151 - 154 (2007/10/02)
The reaction of lithium diphenylcuprate with trans-4- and cis-4-tosyloxy-L-prolines gives excellent yields of 4-phenyl substituted L-prolines and the reaction proceeds with net retention of configuration at the carbon center bearing the tosyloxy group.