103295-95-0

Upstream product

• 454-89-7 3-Trifluoromethylbenzaldehyde 
• 105-45-3 acetoacetic acid methyl ester 

Downstream Products

• 137347-48-9 4-(3-trifluoromethylphenyl)-3-methoxycarbonyl-2,6-dimethyl-1,4-dihydropyridine-5-carboxylic acid 
• 147597-23-7 2,6-Dimethyl-4-(3-trifluoromethyl-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester 

Relevant academic research and scientific papers

Synthesis and antihypertensive activities of new 1,4-dihydropyridine derivatives containing a nitrooxy moiety at the 3-ester position

The synthesis of a new series of dihydropyridines containing a nitrooxy moiety at the 3-ester position is described. The antihypertensive activity of the compounds was examined and compared with that of nifedipine; some of them were relatively potent. The structure-activity relationship is also discussed.