Chemical and Pharmaceutical Bulletin p. 108 - 116 (1993)
Update date:2022-08-04
Topics:
Ogawa
Nakato
Tsuchida
Hatayama
The synthesis of a new series of dihydropyridines containing a nitrooxy moiety at the 3-ester position is described. The antihypertensive activity of the compounds was examined and compared with that of nifedipine; some of them were relatively potent. The structure-activity relationship is also discussed.
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Doi:10.1016/S0040-4020(98)00360-3
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(2008)Doi:10.1016/j.bmc.2008.03.019
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