1033224-86-0

Basic information

• Product Name: N-(3-methoxyphenyl)benzene-1,2-diamine
• Synonyms: N-(3-methoxyphenyl)benzene-1,2-diamine
• CAS NO: 1033224-86-0
• Molecular Weight: 214.267
• Mol File: 1033224-86-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(3-methoxyphenyl)benzene-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-methoxyphenyl)benzene-1,2-diamine(1033224-86-0)
• EPA Substance Registry System: N-(3-methoxyphenyl)benzene-1,2-diamine(1033224-86-0)

Safety Data

• Hazardous Substances Data: 1033224-86-0(Hazardous Substances Data)

Upstream product

• 536-90-3 m-Anisidine 
• 1493-27-2 ortho-nitrofluorobenzene 
• 28093-57-4 (3-methoxy-phenyl)-(2'-nitrophenyl)amine 

Downstream Products

• 581081-50-7 C₁₆H₁₃N₅O₂ 
• 1033224-87-1 1-(3-methoxyphenyl)-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide 

Relevant articles and documents

Design, synthesis and antifungal evaluation of novel pyrazole carboxamides with diarylamines scaffold as potent succinate dehydrogenase inhibitors

Sixteen novel pyrazole carboxamides with diarylamines scaffold were designed, synthesized and characterized in detail via 1H NMR, 13C NMR and ESI-HRMS. Preliminary bioassays showed that some of the target compounds exhibited good ant

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: Potent and selective p70S6 kinase inhibitors

We report herein the design and synthesis of 4-(benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine derivatives as inhibitors of p70S6 kinase. Screening hits containing the 4-(benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine scaffold were optimized for p70S6K potency and selectivity against related kinases. Structure-based design employing an active site homology model derived from PKA led to the preparation of benzimidazole 5-substituted compounds 26 and 27 as highly potent inhibitors (Ki 100-fold selectivity against PKA, ROCK and GSK3.