1033418-69-7 Usage
General Description
Benzyl 4-chloropyridin-3-ylcarbamate is an organic compound that contains a pyridine ring, a benzyl group, and a carbamate group in its structure. The presence of a chlorine atom signifies that it's a halogenated compound, and its functional group locations make it a significant molecule in the area of pharmaceuticals or agrochemicals. The exact properties such as physical state, color, solubility, melting point or boiling point, and specific uses of this particular chemical aren't commonly reported, suggesting it may be primarily utilized as an intermediate or a precursor in the synthesis of other compounds. As with many such compounds, handling typically needs to follow standard safety procedures to prevent harmful exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 1033418-69-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,3,4,1 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1033418-69:
(9*1)+(8*0)+(7*3)+(6*3)+(5*4)+(4*1)+(3*8)+(2*6)+(1*9)=117
117 % 10 = 7
So 1033418-69-7 is a valid CAS Registry Number.
1033418-69-7Relevant articles and documents
Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold
Nishiguchi, Gisele A.,Burger, Matthew T.,Han, Wooseok,Lan, Jiong,Atallah, Gordana,Tamez, Victoriano,Lindvall, Mika,Bellamacina, Cornelia,Garcia, Pablo,Feucht, Paul,Zavorotinskaya, Tatiana,Dai, Yumin,Wong, Kent
supporting information, p. 2328 - 2332 (2016/04/20)
The Pim proteins (1, 2 and 3) are serine/threonine kinases that have been found to be upregulated in many hematological malignancies and solid tumors. As a result of overlapping functions among the three isoforms, inhibition of all three Pim kinases has become an attractive strategy for cancer therapy. Herein we describe our efforts in identifying potent pan-PIM inhibitors that are derived from our previously reported pyridyl carboxamide scaffold as part of a medicinal chemistry strategy to address metabolic stability.
