1033428-91-9

Upstream product

• 4410-99-5 2-mercaptophenylethane 
• 92972-48-0 2,4-dichlorothiazole-5-carboxaldehyde 

Downstream Products

• 1262897-52-8 C₁₅H₁₁ClN₂O₂S₃ 
• 1262897-66-4 C₁₇H₁₃ClN₂O₄S₃ 
• 1262897-59-5 C₁₉H₁₇ClN₂O₄S₃ 

Relevant academic research and scientific papers

Synthesis and antimicrobial activity of some novel thiazolidine-2,4-dione derivatives

In this study, a series of phenylethylsulfanyl-1,3-thiazolo-thiazolidine-2, 4-dione derivatives (VII a - f, VIIIa - f) and 5-methyl-[1,2,4]triazolyl- sulfanyl-1,3-thiazolo-thiazolidine-2,4-dione derivatives (IX a - f, Xa - f) were synthesized and evaluated for their antibacterial and antifungal activities against S. aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), B. subtilis (ATCC 6633), E. coli ( ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used bacteria. ECV Editio Cantor Verlag.

Synthesis and antidiabetic activity of some new thiazolyl-2,4- thiazolidinediones

In this study, a series of thiazolyl-2,4-thiazolidinediones (VIa-f, VIIa-f and VIIIa-f) was prepared by Knoevenagel reaction of substituted phenacyl-2,4-thiazolidinediones (IVa-f)/substituted benzyl-2,4- thiazolidinediones (Va-f) with chlorothiazolecarbaldehydes (II, III).The prepared compounds were tested for their insulinotropic activities in INS-1 cells. A significant insulinotropic effect was seen with compounds VIa, VIb, VIe, VIIa, VIIb and VIIId. Introducing a 2-[(phenylethyl)thio] group into the thiazole ring increased the biological effect, whereas NO2 groups in phenylacyl or benzyl groups diminished the effects. ECV Editio Cantor Verlag.