1033434-92-2Relevant articles and documents
IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS
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Page/Page column 27, (2010/04/30)
The present invention relates to a series of novel imidazo[1,2-α]pyrrolo[3,2-c]pyridines (or also named 6H-1,3a,6-Tri-aza-αy-indacenes) and derivatives thereof, according to formula: (I); The present invention also relates to processes for the preparation of imidazo[1,2-α]pyrrolo[3,2-c]pyridines, their use as. a, medicine, their use to treat or prevent viral infections and their use to manufacture a medicine to treat or prevent viral infections, particularly infections with viruses belonging to the family of the Flaviviridae and more preferably infections with Bovine Viral Diarrhea virus (BVDV).
Short and efficient access to imidazo[1,2-a]pyrrolo[3,2-c]pyridine derivatives
Gaumet, Vincent,Moreau, Emmanuel,Taleb, Abbass,Leal, Fernand,Neyts, Johan,Paeshuyse, Jan,Lartigue, Claire,Chavignon, Olivier,Gueiffier, Alain,Teulade, Jean-Claude,Métin, Jacques,Chezal, Jean-Michel
supporting information; experimental part, p. 6082 - 6085 (2011/01/04)
Access to N-protected or N-free imidazo[1,2-a]pyrrolo[3,2-c]pyridine derivatives as potential antiviral compounds was achieved in good yields from N-protected 7-amino-8-halo-2-methylimidazo[1,2-a]pyridines by catalytic coupling of terminal acetylenes under mild conditions using [PdCl2(PPh 3)2] or [Cu(Phen)(PPh3)2]NO 3.
