1033596-38-1Relevant academic research and scientific papers
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action
Mincione, Francesco,Benedini, Francesca,Biondi, Stefano,Cecchi, Alessandro,Temperini, Claudia,Formicola, Giuseppe,Pacileo, Ilaria,Scozzafava, Andrea,Masini, Emanuela,Supuran, Claudiu T.
experimental part, p. 3216 - 3221 (2011/07/07)
Several aromatic/heterocyclic sulfonamide scaffolds have been used to synthesize compounds incorporating NO-donating moieties of the nitrate ester type, which have been investigated for the inhibition of five physiologically relevant human carbonic anhydr
NITRATE ESTERS OF CARBONIC ANHYDRASE INHIBITORS
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Page/Page column 64-65, (2008/12/06)
Nitroderivatives of carbonic anhydrase inhibitors having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma, ocular hypertension, age-related macular degeneration, diabetic macular edema, diabetic retinopathy, hypertensive retinopathy and retinal vasculopathies, cancer, epilepsy, high-altitude disorders and neuromuscular diseases.
