10336-24-0

Basic information

• Product Name: 9,10-Dihydro-10-phenylacridine
• Synonyms: 9,10-Dihydro-10-phenylacridine
• CAS NO: 10336-24-0
• Molecular Formula: C₁₉H₁₅N
• Molecular Weight: 0
• Mol File: 10336-24-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 9,10-Dihydro-10-phenylacridine(CAS DataBase Reference)
• NIST Chemistry Reference: 9,10-Dihydro-10-phenylacridine(10336-24-0)
• EPA Substance Registry System: 9,10-Dihydro-10-phenylacridine(10336-24-0)

Safety Data

• Hazardous Substances Data: 10336-24-0(Hazardous Substances Data)

Upstream product

• 88-67-5 2-Iodobenzoic acid 
• 91-40-7 2-(phenylamino)benzoic acid 
• 108-86-1 bromobenzene 
• 578-95-0 10H-acridin-9-one 
• 5472-23-1 10-phenylacridin-9(10H)-one 
• 92-81-9 acridine 
• 71-41-0 pentan-1-ol 
• 75-09-2 dichloromethane 
• 603-34-9 N,N-diphenylaminobenzene 

Downstream Products

• 1252763-56-6 rac-10-phenyl-9-(1'-oxocyclopent-2'-yl)acridane 
• 78943-59-6 N-phenyldibenzazepine 
• 5472-23-1 10-phenylacridin-9(10H)-one 
• 1372853-54-7 dimethyl 2-(10-phenyl-9,10-dihydroacridin-9-yl)malonate 
• 1372853-64-9 9-(nitromethyl)-10-phenyl-9,10-dihydroacridine 

Relevant articles and documents

Direct C(sp3)–H Sulfonylation of Xanthene Derivatives with Sodium Sulfinates by Oxidative Copper Catalysis

By employing a readily available CuCl/DDQ catalyst system, we herein report a direct C(sp3)–H sulfonylation of xanthene derivates with odorless sodium sulfinates. Various 9H-xanthenes, thioxanthenes, and 9,10-dihydroacridines are efficiently transformed into the desired benzylic sulfonyl products via a radical/radical cross-coupling process, proceeding with the merits of broad substrate scope, operational simplicity, good functional group compatibility, and mild reaction conditions.

Oxidative C-H bond functionalization and ring expansion with TMSCHN2: A copper(I)-catalyzed approach to dibenzoxepines and dibenzoazepines

Tricyclic dibenzoxepines and dibenzazepines are important therapeutic agents for the pharmaceutical industry and academic research. However, their syntheses are generally rather tedious, requiring several steps that involve a Wagner-Meerwein-type rearrangement under harsh conditions. Herein, we present the first copper(I)-catalyzed oxidative C-H bond functionalization and ring expansion with TMSCHN2 to yield these important derivatives in a facile and straightforward way. Cut a long story short: Tricyclic dibenzoxepines and dibenzazepines are important therapeutic agents for pharmaceuticals, but their syntheses are generally rather tedious. A copper(I)-catalyzed oxidative C-H bond functionalization and ring expansion sequence with TMSCHN2 has been developed to yield these important derivatives in a facile and straightforward way.

Autoxidative carbon-carbon bond formation from carbonhydrogen bonds

(Figure Presented) Only oxygen and acid! The oxidative coupling of xanthene and other activated benzylic compounds with carbon nucleophiles such as ketones, can be performed under ambient conditions without solvent by simply using oxygen and catalytic amounts of methanesulfonic acid. The proposed reaction mechanism involves substrate activation by formation of hydroperoxides; the method can therefore be regarded as an "autoxidative coupling reaction".