103362-82-9Relevant academic research and scientific papers
Inhibitors of slow reacting substance of anaphylaxis
-
, (2008/06/13)
Novel compounds and compositions which inhibit SRS-A in mammals are disclosed. Methods for preparing said compounds and compositions and methods for their use for treating allergic reactions, inflammation and for reducing the severity of myocardial infarction resulting from heart attack are disclosed. Useful intermediates for preparing said compounds are also disclosed.
Synthesis of butanoic acid 4,4'-[(4E, 6Z, 9Z-pentadecatrien-2-ynylidene)]-bis with leukotriene-like activity: Novel acetylenic acetals and dithioacetals as antagonists of leukotriene-C4
Saksena,Green,Mangiaracina,et al.
, p. 6427 - 6430 (2007/10/02)
A selective exchange reaction of a symmetrical acetal with protected cysteine readily provided two hemi-thioacetals related to leukotriene-E4. Use of acetylene-bis-(diethyl acetal) led to a facile synthesis of the title compound. Its correspond
