103367-73-3

Upstream product

• 121210-56-8 ethyl 8-hydroxy-1,4-dioxaspiro[4.5]dec-7-ene-7-carboxylate 
• 74-88-4 methyl iodide 

Downstream Products

• 97859-87-5 <1R*-<1β,2α,4α,6β,7α,8β(1E,2E,4E,6R*)>>-1-(2,4-dimethoxybenzyl)-3-<1-hydroxy-4-methyl-6-(1,2,7-trimethyl-5-oxo-3,9,10-trioxatricyclo<4.3.1.0(2,4)>dec-8-yl)-2,4-heptadienylidene>-2,4-pyrrolidinedione 
• 103367-89-1 (1R*(1Z),2S*,3R*,4R*,5S*,6R*)-2,4-bis((tert-butyldimethylsilyl)oxy)-1-(3,3-dimethoxy-2-methyl-1-butenyl)-3,5-dimethyl-6-((trimethylsilyl)oxy)cyclohexan-1-ol 
• 103383-26-2 (1R*(1Z),2R*,3R*,4R*,5R*,6S*)-4,6-bis((tert-butyldimethylsilyl)oxy)-1-(3,3-dimethoxy-2-methyl-1-butenyl)-3,5-dimethylcyclohexan-1,2-diol 
• 103367-79-9 (1R*,2R*,3S*,5R*,6S*)-tert-butyldimethyl<(3-((tert-butyldimethylsilyl)oxy)-2,6-dimethyl-5-((trimethylsilyl)oxy)-4-oxo-1-cyclohexyl)oxy>silane 
• 103367-78-8 (3R*,4R*,5R*,6S*)-<(3,5-dimethyl-4,6-bis((tert-butyldimethylsilyl)oxy)-1-cyclohexenyl)oxy>trimethylsilane 
• 103383-25-1 (1R*,2S*,3S*,5R*,6R*)-tert-butyldimethyl<(3-((tert-butyldimethylsilyl)oxy)-2,6-dimethyl-5-hydroxy-4-oxo-1-cyclohexyl)oxy>silane 
• 103367-77-7 (1R*,2R*,3S*,6R*)-tert-butyldimethyl<(3-((tert-butyldimethylsilyl)oxy)-2,6-dimethyl-4-oxo-1-cyclohexyl)oxy>silane 
• 103421-92-7 (3R*,4S*,5S*)-<(3,5-dimethyl-4-((tert-butyldimethylsilysl)oxy)-1-cyclohexenyl)oxy>trimethylsilane 
• 103367-76-6 (1R*,2S*,3S*,6R*)-tert-butyldimethyl<(2,6-dimethyl-3-hydroxy-4-oxocyclohexyl)oxy>silane 
• 556051-32-2 (2R,3R,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxy-3,5-dimethyl-cyclohexanone 
• 103367-75-5 (1s,2R,6S)-tert-butyldimethyl<(2,6-dimethyl-4-oxo-1-cyclohexyl)oxy>silane 
• 851530-80-8 (3α,4α,5α)-4-chloro-3,5-dimethylcyclohexanone 
• 851598-24-8 (3α,4β,5α)-4-chloro-3,5-dimethylcyclohexanone 
• 851598-22-6 (3α,4β,5α)-4-hydroxy-3,5-dimethylcyclohexanone 

Relevant academic research and scientific papers

Enantioselective synthesis of the C1-C11 fragment of bafilomycin A1 using non-wittig and desymmetrization strategies

The synthesis of the C1-C11 fragment 33 of bafilomycin A1 was achieved. Intermediate ketone 16 was prepared in six steps from 4-oxopimelate 13. Desymmetrization of this ketone using Koga's chiral base followed by TMSCl quench furnished silyl en