1033701-18-6

Upstream product

• 96606-95-0 3-(2-iodophenyl)propanoic acid 
• 5159-41-1 2-iodobenzyl alcohol 
• 897660-99-0 3-(2-iodophenyl)propanoyl chloride 
• 55223-26-2 3-(2-bromophenyl)propanamide 
• 90725-40-9 3-(2-bromophenyl)propanoyl chloride 
• 15115-58-9 3-(2-bromophenyl)propionic acid 

Downstream Products

• 1423780-87-3 1-(2,6-dimethylphenylimino)-1,2,4,5-tetrahydrobenzo[c]azepin-3-one 
• 1423780-88-4 2-(2-cyanoethyl)-N-(2,6-dimethylphenyl)benzamide 
• 1423780-91-9 [Pd{κ²C,O-C(Ph)=C(Ph)C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)](triflate) 
• 1423780-94-2 [Pd{κ²C,O-C(C₆H₄ⁿBu-4)=C(C₆H₄ⁿBu-4)C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)](triflate) 
• 1423780-98-6 [Pd{κ²C,O-C(C₆H₄Br-4)=C(C₆H₄Br-4)C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)](triflate) 
• 1423781-05-8 (Z)-6,7-diphenyl-1,2-dihydro-4H-benzo[e]azonine-3,5-dione 
• 1423780-75-9 [Pd{C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)] 

Relevant academic research and scientific papers

Palladium-Catalyzed, Norbornene-Mediated, ortho-Amination ipso-Amidation: Sequential C-N Bond Formation

A palladium-catalyzed, norbornene-mediated ortho- and ipso-C-N bond-forming Catellani reaction is reported. This reaction proceeds through a sequential intermolecular amination followed by intramolecular cyclization of a tethered amide. The products, ortho-aminated dihydroquinolinones, were generated in moderate to good yields and are present in bioactive molecules. This work highlights the challenge of competing intra- vs intermolecular palladium-catalyzed processes.

Synthesis and reactivity of ortho-palladated 3-phenylpropanamides. Insertion of CO, XyNC, and alkynes into the Pd-C bond. Synthesis of seven-and nine-membered palladacycles and benzazepine-and benzazonine-based heterocycles

Aryl palladium complexes [Pd{C6H4(CH 2)2C(O)NRR′)-2}I(tmeda)] [NRR′ = NH 2 (1a), NHMe (1b), NMe2 (1c); tmeda = N,N,N′, N′-tetramethylethylenediamine] are prepared by oxidative addition of t