55223-26-2

Basic information

• Product Name: BenzenepropanaMide, 2-broMo-
• Synonyms: BenzenepropanaMide, 2-broMo-;2-BroMo-benzenepropanaMide;3-(2-bromophenyl)propanamide;3-(2-BROMOPHENYL)PROPANAMIDE(WXG01790)
• CAS NO: 55223-26-2
• Molecular Formula: C₉H₁₀BrNO
• Molecular Weight: 228.0858
• Mol File: 55223-26-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BenzenepropanaMide, 2-broMo-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzenepropanaMide, 2-broMo-(55223-26-2)
• EPA Substance Registry System: BenzenepropanaMide, 2-broMo-(55223-26-2)

Safety Data

• Hazardous Substances Data: 55223-26-2(Hazardous Substances Data)

Upstream product

• 66191-86-4 3-(2-bromophenyl)propanoic acid,methyl ester 
• 201230-82-2 carbon monoxide 
• 2039-88-5 2-bromostyrene 
• 15115-58-9 3-(2-bromophenyl)propionic acid 
• 90725-40-9 3-(2-bromophenyl)propanoyl chloride 

Downstream Products

• 61698-07-5 3-(2-bromo-phenyl)-propionitrile 
• 1445166-50-6 methyl 3-(4-((2-(2-cyanoethyl)phenyl)ethynyl)-2-fluorophenyl)propanoate 
• 1429427-39-3 3-(4-((2-(2-cyanoethyl)phenyl)ethynyl)-2-fluorophenyl)propanoic acid 
• 1423781-05-8 (Z)-6,7-diphenyl-1,2-dihydro-4H-benzo[e]azonine-3,5-dione 
• 1423780-98-6 [Pd{κ²C,O-C(C₆H₄Br-4)=C(C₆H₄Br-4)C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)](triflate) 
• 1423780-94-2 [Pd{κ²C,O-C(C₆H₄ⁿBu-4)=C(C₆H₄ⁿBu-4)C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)](triflate) 
• 1423780-91-9 [Pd{κ²C,O-C(Ph)=C(Ph)C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)](triflate) 
• 1423780-87-3 1-(2,6-dimethylphenylimino)-1,2,4,5-tetrahydrobenzo[c]azepin-3-one 
• 1423780-88-4 2-(2-cyanoethyl)-N-(2,6-dimethylphenyl)benzamide 
• 1423780-75-9 [Pd{C₆H₄(CH₂)₂C(O)NH₂-2}I(N,N,N′,N′-tetramethylethylenediamine)] 
• 1033701-18-6 3-(2-iodophenyl)propanamide 
• 1310552-84-1 N-(3-(2-bromophenyl)propyl)-2,2,2-trifluoro-N-(2-(trimethylsilyl)ethynyl) acetamide 
• 1310552-75-0 N-(3-(2-bromophenyl)propyl)-2,2,2-trifluoroacetamide 

Relevant articles and documents

The Asymmetric Synthesis of 1-Alkyl-2,3,4,5-Tetrahydro-Benzazepines and Benzo-1-AzabicycloDecanes

The metalation-alkylation of benzazepine formamidines gives high yields and good diastereoselectivity of 1-substituted derivatives.Removal of the chiral auxiliary leads to the title compounds in 84-96 percent ee and represents the first chiral benzazepine

Discovery of TUG-770: A highly potent free fatty acid receptor 1 (FFA1/GPR40) agonist for treatment of type 2 diabetes

Free fatty acid receptor 1 (FFA1 or GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and currently attracts high interest as a new target for the treatment of type 2 diabetes. We here report the discovery of a highly potent FFA1 agonist with favorable physicochemical and pharmacokinetic properties. The compound efficiently normalizes glucose tolerance in diet-induced obese mice, an effect that is fully sustained after 29 days of chronic dosing.

Radical cyclization of ynamides into six- or eight-membered rings. Application to the synthesis of a protoberberine analog

A straightforward formation of six- and eight-membered rings via the radical cyclization of specifically designed ynamides is reported. This strategy provides a protoberberine analog in only three steps by a radical cyclization cascade.