1033725-91-5Relevant academic research and scientific papers
Zinc-catalyzed synthesis of pyrazolines and pyrazoles via hydrohydrazination
Alex, Karolin,Tillack, Annegret,Schwarz, Nicolle,Beller, Matthias
, p. 2377 - 2379 (2008)
(Chemical Equation Presented) A novel regioselective synthesis of aryl-substituted pyrazolines and pyrazoles has been developed. Substituted phenylhydrazines react with 3-butynol in the presence of a catalytic amount of zinc triflate to give pyrazoline derivatives. The resulting products are easily oxidized in a one-pot procedure to the corresponding pyrazoles.
