1033752-71-4Relevant academic research and scientific papers
Pd-indenyl-diphosphine: An effective catalyst for the preparation of triarylamines
Yan, Meng-Qi,Yuan, Jia,Pi, Yun-Xiao,Liang, Jin-Hua,Liu, Yan,Wu, Qing-Guo,Luo, Xue,Liu, Sheng-Hua,Chen, Jian,Zhu, Xiao-Lei,Yu, Guang-Ao
, p. 451 - 454 (2015)
A new Buchwald-type diphosphine ligand has been developed for applications in Pd-catalyzed amination reactions towards the preparation of triarylamines. The catalyst can be used to perform the amination of a diverse array of aryl and heteroaryl chlorides.
Pd-catalyzed aryl amination mediated by well defined, N-heterocyclic carbene (NHC)-Pd precatalysts, PEPPSI
Organ, Michael G.,Abdel-Hadi, Mirvat,Avola, Stephanie,Dubovyk, Igor,Hadei, Niloufar,Kantchev, Eric Assen B.,O'Brien, Christopher J.,Sayah, Mahmoud,Valente, Cory
experimental part, p. 2443 - 2452 (2009/04/08)
Pd-N-heterocyclic carbene (NHC)-catalyzed Buchwald-Hartwig animation protocols mediated by Pd-PEPPSI precatalysts is described. These protocols provide access to a range of hindered and functionalized drug-like aryl amines in high yield with both electron-deficient and electron-rich aryl- and heteroaryl chlorides and bromides. Variations in solvent polarity, base and temperature are tolerated, enhancing the scope and utility of this protocol. A mechanistic rationalization for base strength (pKb) requirements is also provided.
