1033804-52-2Relevant academic research and scientific papers
Synthesis of some new 1-(6-fluorobenzothiazol-2-yl)-3-(4-fluoro- phenyl)-5-arylpyrazolines and their iodine(III) mediated oxidation to corresponding pyrazoles
Aggarwal, Ranjana,Kumar, Vinod,Singh, Shiv P
, p. 1332 - 1336 (2008/09/18)
The reaction of fluorinated chalcones 2 and 6-fluorobenzothiazol-2- ylhydrazine 1 in presence of catalytic amount of glacial acetic acid in refluxing ethanol yields l-(6-fluorobenzothiazol-2-yl)-3-(4-fluorophenyl)-5- arylpyrazolines 3, which undergo facile oxidation to the corresponding pyrazoles 4 in good yield using iodobenzene diacetate (IBD). The structures of the synthesized compounds have been established on the basis of their elemental analysis, MS and 1H and 13C NMR spectroscopy.
