1034021-65-2Relevant academic research and scientific papers
Development of a practical and scalable synthesis of a potent CRTH2 antagonist
Yoshida, Shinya,Yoshino, Toshitaka,Miyafuji, Akio,Yasuda, Hironobu,Kimura, Takenori,Takahashi, Takumi,Mukuta, Takashi
, p. 1544 - 1551 (2013/02/23)
This contribution describes the process research and development of a practical and scalable synthetic method towards compound 1, which has a potent CRTH2 antagonistic activity. The medicinal chemistry synthetic route and second generation synthetic route
