103408-59-9Relevant academic research and scientific papers
PARTIAL PROTECTION OF CARBOHYDRATE DERIVATIVES. PART 18. SIMPLE, PREPARATIVE PROCEDURE FOR 5'-O-ACYLRIBONUCLEOSIDES; HIGHLY REGIOSELECTIVE O-DEACyLATION AT 2' AND 3' POSITIONS OF FULLY ACYLATED PURINE AND PYRIMIDINE RIBONUCLEOSIDE THROUGH SODIUM METHOXYDE-THF SYSTEM
Nishino, Shigeyoshi,Rahman, MD. Azizur,Takamura, Hatsuko,Ishido, Yoshiharu
, p. 5503 - 5506 (2007/10/02)
A treatment of fully acylated purine and pyrimidine ribonucleosides with a small excess amount of sodium methoxide in THF at room temperature gave the corresponding 5'-acylates in excellent yields; N-acyl groups on the nucleic acid base moieties of adenosine and cytidine in addition to guanosine derivatives satisfactorily survived under the conditions used.
