103412-30-2

Upstream product

• 108-24-7 acetic anhydride 
• 86996-95-4 (S)-5-methyl-3-(1,2,2-trimethylcyclopentyl)benzene-1,2-diol 
• 103412-32-4 1,2-dibenzoyloxyherbertene 
• 86996-97-6 14-hydroxy-1-methoxyherbertene 
• 86996-96-5 1,14-dihydroxyherbertene 
• 87016-04-4 1,14-epoxyherbertene 
• 81784-10-3 4-methyl-2-[(1S)-1,2,2-trimethylcyclopentyl]phenol 
• 86996-98-7 14-ethylthio-1-hydroxyherbertene 
• 86996-94-3 (-)-herbertenolide 

Relevant academic research and scientific papers

Cytotoxic, radical scavenging and antimicrobial activities of sesquiterpenoids from the Tahitian liverwort Mastigophora diclados (Brid.) Nees (Mastigophoraceae)

A drimane, (+)-drimenol (1), five known herbertanes, (-)-α- herbertenol (2), (-)-herbertenediol (3), mastigophorene A (4), (-)-mastigophorene C (5) and (-)-mastigophorene D (6), a pimarane, (-)-e nt-pimara-8(14),15-dien-19-oic acid (7), and two eudesmanolides, (-)-diplophyllolide A (8) and (-)-diplophyllin (9) were isolated from the Tahitian Mastigophora diclados (Brid.) Nees. Herbertane sesquiterpenes (2, 3, 5 and 6) showed cytotoxicity against HL-60 and KB cell lines, radical scavenging activity and antimicrobial activity against Bacillus subtilis. (-)-Diplophyllolide A (8) also exhibited cytotoxicity against HL-60 and KB cell lines.

Structures of ent-Herbertane Sesquiterpenoids displaying Antifungal Properties from the Liverwort Herberta adunca

Several aromatic sesquiterpenoids displaying antifungal propaerties have been isolated from the liverwort Herberta adunca together with a mother hydrocarbon with a novel irregular sesquiterpene skeleton, ent-herbertane, and their structures and absolute configurations have been determined on the basis of extensive degradation reactions and spectroscopic evidence.The biological activity is also described.