103422-95-3

Basic information

• Product Name: (R)-4-isopropyl-3-(2-phenylacetyl)oxazolidin-2-one
• Synonyms: (R)-4-isopropyl-3-(2-phenylacetyl)oxazolidin-2-one
• CAS NO: 103422-95-3
• Molecular Weight: 247.294
• Mol File: 103422-95-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (R)-4-isopropyl-3-(2-phenylacetyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-isopropyl-3-(2-phenylacetyl)oxazolidin-2-one(103422-95-3)
• EPA Substance Registry System: (R)-4-isopropyl-3-(2-phenylacetyl)oxazolidin-2-one(103422-95-3)

Safety Data

• Hazardous Substances Data: 103422-95-3(Hazardous Substances Data)

Upstream product

• 17016-83-0 (4S)-4-isopropyl-1,3-oxazolidin-2-one 
• 501-53-1 benzyl chloroformate 
• 103-82-2 phenylacetic acid 
• 95530-58-8 (R)-4-isopropyloxazolidin-2-one 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 103422-96-4 (4R,2'R)-3-<2-(((benzyloxy)carbonyl)oxy)-2-phenyl-1-oxoethyl>-4-isopropyloxazolidin-2-one 
• 161745-68-2 (2S,3S)-1,4-Bis-((S)-4-isopropyl-2-oxo-oxazolidin-3-yl)-2,3-diphenyl-butane-1,4-dione 
• 214492-01-0 (4S,2'S)-4-isopropyl-3-(2'-phenylpropanoyl)oxazolidin-2-one 
• 214492-04-3 (4R)-4-isopropyl-3-[(2S)-2-phenylpropionyl]oxazolidin-2-one 
• 311310-18-6 (4S,2'R)-4-iso-propyl-3-(2'-phenylpropionyl)oxazolidin-2-one 
• 311310-15-3 (4S,2'S)-4-iso-propyl-3-(2'-phenylpropionyl)oxazolidin-2-one 
• 74431-38-2 (2S,3S)-(+)-2,3-Diphenylsuccinic acid 
• 1378315-02-6 (S)-tert-butyl 4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)-4-oxo-3-phenylbutanoate 
• 1378314-76-1 (S)-1-tert-butyl 4-(2,6-dimethylphenyl) 2-phenylsuccinate 
• 1378314-77-2 (S)-4-tert-butyl 1-(2,6-dimethylphenyl) 2-phenylsuccinate 
• 1378315-03-7 (S)-4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)-4-oxo-3-phenylbutanoic acid 
• 1378315-05-9 (S)-2,6-dimethylphenyl 4-((S)-4-isopropyl-2-oxooxazolidin-3-yl)-4-oxo-3-phenylbutanoate 
• 1378315-09-3 (S)-4-(2,6-dimethylphenoxy)-4-oxo-2-phenylbutanoic acid 

Relevant articles and documents

Ni-Catalyzed Regiodivergent and Stereoselective Hydroalkylation of Acyclic Branched Dienes with Unstabilized C(sp3) Nucleophiles

Two complementary regiodivergent [(P,N)Ni]-catalyzed hydroalkylations of branched dienes are reported. When amides are employed as unstabilized C(sp3) nucleophiles, a highly regioselective 1,4-addition process is favored. The addition products are obtained in high yield and with excellent stereocontrol of the internal olefin. With use of a chiral ligand and imides as carbon nucleophiles, a 3,4-addition protocol was developed, enabling construction of two contiguous tertiary stereocenters in a single step with moderate to high levels of diastereocontrol and excellent enantiocontrol. Both methods operate under mild reaction conditions, display a broad scope, and show excellent functional group tolerance. The synthetic potential of the 3,4-hydroalkylation reaction was established via a series of postcatalytic modifications.

Preparation of chiral 3-arylpyrrolidines via the enantioselective 1,4-addition of arylboronic acids to fumaric esters catalyzed by Rh(I)/chiral diene complexes

A highly efficient rhodium-catalyzed protocol for the preparation of 2-arylsuccinic esters and 3-arylpyrrolidines of high optical purity has been achieved. In the presence of 1 mol % of a chiral diene/Rh(I) catalyst, asymmetric addition of various arylbor

A convenient method for synthesis of optically active methylphenidate from N-methoxycarbonylpiperidine by utilizing electrochemical oxidation and Evans aldol-type reaction

A new method to prepare optically active methylphenidate starting from piperidine is described. The method consists of a transformation of N-methoxycarbonylated piperidine to the corresponding α-methoxylated carbamate utilizing electrochemical oxidation f