10344-42-0

Basic information

• Product Name: 4-Bromo-3,6-dichloropyridazine
• Synonyms: 4-Bromo-3,6-dichloropyridazine;Pyridazine, 4-broMo-3,6-dichloro-;3,6-Dichoro-4-bromopyridrazine
• CAS NO: 10344-42-0
• Molecular Formula: C₄HBrCl₂N₂
• Molecular Weight: 227.876
• Mol File: 10344-42-0.mol
• Article Data: 10

Chemical Properties

• Melting Point: 80-81 °C
• Boiling Point: 341.794 °C at 760 mmHg
• Flash Point: 160.512 °C
• Appearance: /
• Density: 1.965 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.72±0.10(Predicted)
• CAS DataBase Reference: 4-Bromo-3,6-dichloropyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-3,6-dichloropyridazine(10344-42-0)
• EPA Substance Registry System: 4-Bromo-3,6-dichloropyridazine(10344-42-0)

Safety Data

• Hazardous Substances Data: 10344-42-0(Hazardous Substances Data)

Usage

General Description

4-Bromo-3,6-dichloropyridazine is a synthetic organic compound with the molecular formula C4HBrCl2N2. The systematic name of this chemical compound is 4-bromo-3,6-dichloropyridazin-1-ium. It appears as an off-white or slightly yellow crystalline powder and is highly soluble in water. It has various industrial and laboratory applications, particularly in pharmaceutical, agrochemical, and material science. It is also used as a building block in the synthesis of other chemicals. Despite its various uses, it can be harmful if swallowed, inhaled, or in contact with the skin, and may also cause serious eye damage. Therefore, it is necessary to handle it with care, following all safety protocols.

InChI:InChI=1/C4HBrCl2N2/c5-2-1-3(6)8-9-4(2)7/h1H

Upstream product

• 15456-86-7 4-bromo-1,2-dihydropyridazine-3,6-dione 

Downstream Products

• 823-58-5 3,6-dichloropyridazin-4-amine 
• 10344-41-9 2-[(3,6-dichloropyridazine-4-yl)thio]aniline 
• 21415-33-8 3,6-dichloro-4-pyrrolidin-1-yl-pyridazine 

Relevant articles and documents

Synthesis of new derivatives of 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines

New 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines were prepared and evaluated for inhibitory activity against soybean 15-lipoxygenase enzyme. These compounds were synthesized by the sequential treatment of 4-bromo-3,6-dichloropyridazine with 2-aminothiophenol and a secondary amine with the subsequent heterocyclization in the presence of sodium amide.

PYRROLO-QUINOXALINONE DERIVATIVES AS ANTIBACTERIALS

Tricyclic nitrogen containing compounds of the following Formula (I) and their use as antibacterials.

Triazolo-pyridazine derivatives as ligands for GABA receptors

1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-alkoxy moiety at the 6-position, are selective ligands for GABAAreceptors, in particular having high affinity for the α2