1034620-65-9Relevant academic research and scientific papers
Intermolecular C(sp3)?H Amination Promoted by Internal Oxidants: Synthesis of Trifluoroacetylated Hydrazones
Zhu, Chuanle,Zeng, Hao,Chen, Fulin,Yang, Zhiyi,Cai, Yingying,Jiang, Huanfeng
, p. 17215 - 17219 (2018)
An intermolecular C(sp3)?H amination reaction is reported that is promoted by internal oxidants and occurs via a C=N bond formation step. This intermolecular C(sp3)?H amination reaction of trifluoromethyl ketones and aryldiazonium tetrafluoroborates affords various valuable trifluoroacetylated hydrazones in high yields with excellent E/Z selectivities. The salient features of this reaction type is that it is free of metal, catalyst, directing groups, and azides, and that it can be carried out under mild conditions, is operationally simple and efficient, gram-scalable, and it tolerates various functional groups. Remarkably, an ectoparasites-controlling agent was smoothly synthesized on a gram scale using our method. Aryldiazonium tetrafluoroborates served as the aminating reagents as well as an internal oxidant.
Synthesis method of 3-(trifluoroacetyl)indazole derivative
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Paragraph 0066-0079, (2019/01/23)
The invention belongs to the technical field of organic synthesis and discloses a synthesis method of a 3-(trifluoroacetyl)indazole derivative. The method comprises the following steps: 2,6-dichloro-4-trifluoromethylaniline are stirred with water, ethanol
ORGANIC COMPOUNDS
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, (2008/12/06)
The invention relates to compounds of the general formula (I), wherein R1, R2, Q, X, m and n have the meanings given in the claims, and optionally the enantiomers thereof. The active ingredients have advantageous pesticidal properties. They are especially suitable for controlling parasites on warm-blooded animals and plants.
