1034852-92-0

Basic information

• Product Name: methyl 2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-2-p-tolylacetate
• Synonyms: methyl 2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-2-p-tolylacetate
• CAS NO: 1034852-92-0
• Molecular Weight: 304.299
• Mol File: 1034852-92-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-2-p-tolylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-2-p-tolylacetate(1034852-92-0)
• EPA Substance Registry System: methyl 2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)-2-p-tolylacetate(1034852-92-0)

Safety Data

• Hazardous Substances Data: 1034852-92-0(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 34966-53-5 methyl 4-methylphenylglyoxylate 

Downstream Products

• 1034853-37-6 (S)-methyl 2-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-2-p-tolylbutanoate 

Relevant articles and documents

Asymmetric synthesis of carboxylic acid derivatives having an all-carbon α-quaternary center through Cu-catalyzed 1,4-addition of dialkylzinc reagents to 2-aryl acetate derivatives

(Chemical Equation Presented) The asymmetric synthesis of carboxylic acid derivatives having an all-carbon α-quaternary center has been achieved via copper-catalyzed 1,4-addition of dialkylzinc reagents to aryl acetate derivatives in the presence of phosphoramidite ligand. High isolated yields and enantioselectivities were obtained. It was demonstrated that the Meldrum's acid and ester moieties present on the all-carbon quaternary center allow for a wide variety of subsequent transformations, leading to the expedient preparation of succinimides, succinate esters and succinic acids, γ-butyrolactones, and β-amino acid derivatives.