1034890-95-3Relevant academic research and scientific papers
Chemical and biological investigation of cyclopropyl containing diaryl-pyrazole-3-carboxamides as novel and potent cannabinoid type 1 receptor antagonists
Szabó, Gyorgy,Varga, Balázs,Páyer-Lengyel, Dóra,Szemzo, Attila,Erdélyi, Péter,Vukics, Krisztina,Szikra, Judit,Hegyi, éva,Vastag, Mónika,Kiss, Béla,Laszy, Judit,Gyertyán, István,Fischer, János
supporting information; experimental part, p. 4329 - 4337 (2010/02/28)
Obesity is a major clinical problem in the western world, and many molecular targets have been explored in the search for effective therapeutic agents. One of these, antagonism of the cannabinoid 1 (CB1) receptor, rose to prominence following reports demo
NOVEL CB1 ANTAGONISTS AND THEIR PREPARATION
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Page/Page column 14, (2008/12/06)
The invention relates to new compounds of general formula (I) acting as CB1 antagonists and to their preparation. The compounds according to this invention can be used for the treatment of obesity, behavioral addictions, psychiatric and metabolic disorder
