1035-93-4

Basic information

• Product Name: 5-(1-Naphtyl)-3-phenylisoxazole
• Synonyms: 5-(1-Naphtyl)-3-phenylisoxazole
• CAS NO: 1035-93-4
• Molecular Formula: C₁₉H₁₃NO
• Molecular Weight: 0
• Mol File: 1035-93-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(1-Naphtyl)-3-phenylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1-Naphtyl)-3-phenylisoxazole(1035-93-4)
• EPA Substance Registry System: 5-(1-Naphtyl)-3-phenylisoxazole(1035-93-4)

Safety Data

• Hazardous Substances Data: 1035-93-4(Hazardous Substances Data)

Upstream product

• 90-14-2 1-Iodonaphthalene 
• 199620-14-9 chromium⁽⁰⁾ hexacarbonyl 
• 536-74-3 phenylacetylene 
• 35330-76-8 2-methanesulfinylnaphthalene 
• 29526-96-3 1-phenylcyclopropan-1-ol 
• 80674-36-8 3-(naphthalen-1-yl)-1-phenylprop-2-en-1-one 
• 16736-86-0 1-(naphthalen-1-yl)-3-phenylprop-2-yn-1-one 
• 66-77-3 1-naphthaldehyde 

Relevant articles and documents

Metal-Free Cyclopropanol Ring-Opening C(sp3)-C(sp2) Cross-Couplings with Aryl Sulfoxides

A metal-free method for formal β-arylation/heteroarylation of ketones through efficient cyclopropanol ring-opening cross-couplings with aryl sulfoxides at room temperature has been developed. This protocol shows a broad substrate scope and promising scalability. In addition, the utility of the β-arylated ketones is further demonstrated through a variety of postcoupling transformations and synthetic applications.

Phosphine- and copper-free palladium catalyzed one-pot four-component carbonylation reaction for the synthesis of isoxazoles and pyrazoles

The palladium catalyzed one-pot synthesis of isoxazoles and pyrazoles from aryl iodides, terminal alkynes, chromium hexacarbonyl and hydroxylamine hydrochloride or aqueous hydrazine solution is described. The Sonogashira carbonylative coupling intermediate was trapped in situ by hydroxylamine hydrochloride or aqueous hydrazine to deliver isoxazoles or pyrazoles, respectively, in high yields. This efficient method proceeds at atmospheric pressure and moderate temperature and does not require the use of copper, phosphine ligands or gaseous carbon monoxide.