103502-52-9

Upstream product

• 21577-50-4 mucobromic acid 
• 100-51-6 benzyl alcohol 
• 766-38-1 mucobromic acid 

Downstream Products

• 853644-88-9 2,3-bis-(1-benzenesulfonyl-1H-indol-3-yl)-4-benzyloxy-2-buten-4-olide 
• 1386385-96-1 5-benzyloxy-3-bromo-4-phenylaminofuran-2(5H)-one 
• 1386385-97-2 5-benzyloxy-3-bromo-4-(4-methoxyphenyl)aminofuran-2(5H)-one 
• 1386385-98-3 5-benzyloxy-3-bromo-4-(3,4-dimethylphenyl)aminofuran-2(5H)-one 
• 1386385-99-4 5-benzyloxy-3-bromo-4-(4-fluorophenyl)aminofuran-2(5H)-one 
• 1386386-00-0 5-benzyloxy-3-bromo-4-(4-chlorophenyl)aminofuran-2(5H)-one 
• 1386386-01-1 5-benzyloxy-3-bromo-4-(4-bromophenyl)aminofuran-2(5H)-one 
• 1386386-02-2 5-benzyloxy-3-bromo-4-(3-chlorophenyl)aminofuran-2(5H)-one 
• 1386386-03-3 5-benzyloxy-3-bromo-4-(naphthalen-1-ylamino)furan-2(5H)-one 
• 1386386-04-4 5-benzyloxy-3-bromo-4-(4-methylbenzyl)aminofuran-2(5H)-one 
• 1386386-05-5 5-benzyloxy-3-bromo-4-(4-methoxybenzyl)aminofuran-2(5H)-one 
• 1386386-06-6 5-benzyloxy-3-bromo-4-(2-chlorobenzyl)aminofuran-2(5H)-one 
• 1386386-07-7 4-benzylamino-5-benzyloxy-3-bromofuran-2(5H)-one 

Relevant academic research and scientific papers

Preparation of aryl-substituted butenolides using mucohalic acids

Methods and materials for preparing 3-aryl-2-buten-4-olides and 2,3-bisaryl-2-buten-4-olides are disclosed. The methods include reacting a mucohalic acid with a reducing agent to give a 2,3-dihalo-2-buten-4-olide, which undergoes at least one Pd catalyzed cross-coupling reaction with an arylboronic acid.

Process for preparing highly functionalized gamma-butyrolactams and gamma-amino acids

The invention relates to a process for preparing highly functionalized γ-butyrolactams and γ-amino acids by reductive amination of mucohalic acid or its derivatives, and discloses a process for preparing pregabalin, a GABA analog with desirable medicinal activity.