1035079-85-6

Basic information

• Product Name: 1-(4'-methoxyphenyl)-1.3-dihydroisobenzofuran-5-ol
• Synonyms: 1-(4'-methoxyphenyl)-1.3-dihydroisobenzofuran-5-ol
• CAS NO: 1035079-85-6
• Molecular Weight: 242.274
• Mol File: 1035079-85-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(4'-methoxyphenyl)-1.3-dihydroisobenzofuran-5-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4'-methoxyphenyl)-1.3-dihydroisobenzofuran-5-ol(1035079-85-6)
• EPA Substance Registry System: 1-(4'-methoxyphenyl)-1.3-dihydroisobenzofuran-5-ol(1035079-85-6)

Safety Data

• Hazardous Substances Data: 1035079-85-6(Hazardous Substances Data)

Upstream product

• 620-24-6 3-Hydroxybenzyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1263748-91-9 C₁₅H₁₂O₄ 

Relevant articles and documents

A simple and efficient large-scale synthesis of 3-hydroxyphthalans via oxa-Pictet-Spengler reaction catalyzed by nanosilica sulfuric acid

Nanosilica sulfuric acid is found to be a new, powerful and reusable heterogeneous catalyst for the rapid synthesis of 3-hydroxyphthalans via condensation of aromatic aldehydes and 3-hydroxybenzyl alcohols under conventional heating and microwave irradiat

The oxa-Pictet-Spengler reaction: A highlight on the different efficiency between isochroman and phthalan or homoisochroman derivative syntheses

Recently we reported that 6-hydroxy- and 6,7-dihydroxy-isochromans can be obtained under very mild conditions and with very good yield by a one-pot synthesis based on a modified oxa-Pictet-Spengler reaction. In this paper, we demonstrate that the above reaction is also useful for the synthesis of hydroxyphthalans, and we discuss the effects of the substituents on the alcoholic aromatic ring on the course of the reaction, as well as those on the aldehydic structure. We also report a synthesis of hydroxyhomoisochromans performed by the same method. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.