1035229-55-0

Upstream product

• 60-12-8 2-phenylethanol 
• 155526-40-2 3-phenethoxypropanoic acid 

Downstream Products

• 215036-15-0 2-Methyl-2-(3-phenethyloxy-propionylamino)-propionic acid 
• 925244-35-5 N-(2-dimethylaminoethyl)-N-(2-hydroxyethyl)-3-phenethyloxy-propanamide 
• 928663-69-8 N-butyl-N-(2-hydroxy-ethyl)-3-phenethyloxy-propionamide 
• 925244-19-5 N-(2-diethylaminoethyl)-N-(2-hydroxyethyl)-3-phenethyloxy-propanamide 
• 155526-41-3 N-(2,2-dimethoxy-ethyl)-N-methyl-3-phenethyloxy-propionamide 
• 925242-73-5 N-benzyl-N-(2,2-diethoxyethyl)-3-phenethyloxy-propanamide 
• 925244-07-1 tert-butyl 4-{(2-hydroxyethyl)[3-(2-phenylethoxy)propanoyl]amino}piperidine-1-carboxylate 
• 1314899-82-5 C₂₆H₃₅N₃O₄S 
• 928663-70-1 N-butyl-N-(2-oxo-ethyl)-3-phenethyloxy-propionamide 
• 1035229-56-1 (R)-N-sec-butyl-N-(2,2-dimethoxyethyl)-3-phenethoxypropanamide 
• 925242-55-3 N-(2,2-diethyloxyethyl)-N-phenethyl-3-phenethyloxy-propanamide 
• 925242-29-1 tert-butyl 4-({(2-hydroxyethyl)[3-(2-phenylethoxy)propanoyl]amino}-methyl)piperidine-1-carboxylate 
• 925243-71-6 N-(2,2-diethoxyethyl)-3-phenethyloxy-N-(5-phenethyloxypentyl)propanamide 
• 925243-47-6 N-(3,3-diethoxypropyl)-N-phenethyl-3-phenethyloxy-propanamide 

Relevant academic research and scientific papers

The chemistry of 2-alkenyl-5(4H)-oxazolones. VIII acid-catalyzed reaction with alcohols

The acid-catalyzed reaction of 4,4-dimethyl-2-vinyl-5(4H)-oxazolone with primary alcohols proceeded with almost equal frequency at both C=C (Michael addition) and C=O (ring opening) groups; reaction with secondary and tertiary alcohols resulted in a modes

Design driven HtL: The discovery and synthesis of new high efficacy β2-agonists

The design and synthesis of a new series of high efficacy β2-agonists devoid of the key benzylic alcohol present in previously described highly efficacious β2-agonists is reported. A hypothesis for the unprecedented level of efficacy is proposed based on considerations of β2-adrenoceptor crystal structure, other biophysical data and modeling studies.

AMINE DERIVATIVES AND THEIR USE IN BETA-2-ADRENORECEPTOR MEDIATED DISEASES

The present invention provides compounds of formula (I), wherein k, Ar, R2, R3, R4, R5, R4', R5', R6, R7, A, D, m and E are as defined in the specification, processes

NOVEL BENZOTHIAZOLONE DERIVATIVES

The present invention provides compounds of formula (I) wherein e, R1, R2, R3, R4, R5, R4, R5, R6, R7, R7a, R7b, A, D, m and n are as

7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS

The present invention provides compounds of formula (I) wherein e, R1, R2, R3, R4, R5, R4', R5', R6, R7, A, D, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.