1035235-29-0

Basic information

• Product Name: 4-Cyano-2-fluorobenzeneboronic acid, pinacol ester
• Synonyms: 4-Cyano-2-fluorobenzeneboronic acid, pinacol ester;3-Fluoro-4-(4,4,5,5-tetramethyl-1,3-dioxaborolan-2-yl)benzonitrile
• CAS NO: 1035235-29-0
• Molecular Formula: C₁₃H₁₅BFNO₂
• Molecular Weight: 247.0731032
• Mol File: 1035235-29-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Cyano-2-fluorobenzeneboronic acid, pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cyano-2-fluorobenzeneboronic acid, pinacol ester(1035235-29-0)
• EPA Substance Registry System: 4-Cyano-2-fluorobenzeneboronic acid, pinacol ester(1035235-29-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 1035235-29-0(Hazardous Substances Data)

Usage

General Description

4-Cyano-2-fluorobenzeneboronic acid, pinacol ester is a chemical compound with the formula C14H16BNO3. It is a boronic acid pinacol ester derivative, which means it contains a boronic acid functional group and a pinacol ester moiety. 4-Cyano-2-fluorobenzeneboronic acid, pinacol ester is commonly used in organic synthesis as a building block for the development of various pharmaceuticals, agrochemicals, and materials. It can also be utilized as a reagent in Suzuki-Miyaura coupling reactions to form carbon-carbon bonds, and in the synthesis of biaryl compounds. Additionally, it has potential applications in medicinal chemistry and drug discovery due to its ability to selectively modify biological targets with minimal side effects. Overall, 4-Cyano-2-fluorobenzeneboronic acid, pinacol ester is a versatile and valuable chemical compound in the field of organic and pharmaceutical chemistry.

Upstream product

• 133059-44-6 4-bromo-3-fluorobenzonitrile 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1255869-47-6 N-((5-(4-cyano-2-fluorophenyl)pyridin-3-yl)(cyclopropyl)methyl)ethanesulfonamide 
• 1363148-60-0 3-fluoro-4-(2-methylpyridin-4-yl)benzonitrile 
• 1352812-53-3 C₂₅H₂₅FN₄O₄S 
• 1352813-03-6 C₂₀H₁₇FN₄O₂S*ClH 
• 1352812-55-5 C₂₅H₂₃FN₄O₄S 
• 1308669-18-2 3-fluoro-4-[4-(1-hydroxy-ethyl)-pyridin-3-yl]-benzonitrile 

Relevant articles and documents

INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE

Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.

ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE

An organic electroluminescence device includes a first electrode, a hole transport region disposed on the first electrode, an emission layer disposed on the hole transport region, an electron transport region disposed on the emission layer, and a second electrode disposed on the electron transport region, wherein the emission layer includes a polycyclic compound containing two electron donors and one electron acceptor, and the electron acceptor includes a benzonitrile part and a pyridine part, thereby showing high emission efficiency.

HETEROCYCLIC COMPOUND AND USE THEREOF

The present invention provides a heterocycle derivative having a superior amyloid β production inhibitory activity and/or a superior γ-secretase modulation activity, and use thereof. A compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a salt thereof.