10353-44-3

Upstream product

• 100-44-7 benzyl chloride 
• 10512-65-9 4H-2,3-dihydro-1,3-benzothiazine-2,4-dione 
• 100-46-9 benzylamine 
• 2527-62-0 bis[2-(N-benzylcarbamoyl)phenyl] disulfide 
• 119-80-2 2,2'-dithiobenzoic acid 
• 147-93-3 Thiosalicylic acid 
• 92432-91-2 (4-oxo-4H-benzo[e][1,3]thiazin-2-yl)-guanidine 
• 15601-85-1 4H-2,3-dihydro-2-imino-1,3-benzothiazin-4-one 

Relevant academic research and scientific papers

N-alkylation of imides using phase transfer catalysts under solvent-free conditions

(Chemical Equation Presented) N-Alkylation of imides in the reaction of imides and alkylhalides, catalyzed by PT catalysts under solvent-free conditions, has been developed. The reaction occurs in the presence of K 2CO3, and in many cases it takes place spontaneously. In the N-benzylation reaction, it has been recognized that TBAB (tetrabutylammonium bromide) and TBATFB (tetrabutylammonium tetrafluoroborate) show highest catalytic effect. Versatility and synthetic capacity of the solvent-free alkylation has been confirmed by N-benzylation and N-ethylation of various imides. The developed procedure gives easy access to N-(ω-bromoalkyl) imides.

A simple one-pot synthesis of benzoxazine-2,4-diones and benzothiazine-2,4-diones

A simple and efficient procedure has been developed for a one-pot synthesis of substituted benzoxazine-2,4-diones and benzothiazine-2,4-diones directly from salicylic acid (or thiosalicylic acid) and amines.