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1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1035348-70-9

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1035348-70-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1035348-70-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,5,3,4 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1035348-70:
(9*1)+(8*0)+(7*3)+(6*5)+(5*3)+(4*4)+(3*8)+(2*7)+(1*0)=129
129 % 10 = 9
So 1035348-70-9 is a valid CAS Registry Number.

1035348-70-9Downstream Products

1035348-70-9Relevant academic research and scientific papers

METHODS OF USING COMBINATIONS OF MEK AND JAK-2 INHIBITORS

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Page/Page column 191, (2008/12/04)

A method of treating a disease in a mammal, comprising administering to the mammal a therapeutically effective amount of a MEK compound of Formula I(M), or a pharmaceutical composition comprising a therapeutically effective amount of a MEK compound of Formula I(M) and a pharmaceutically acceptable carrier, in combination with a therapeutically effective amount of a JAK-2 compound of Formula I(J), or a pharmaceutical composition comprising a therapeutically effective amount of a JAK-2 compound of Formula I(J) and a pharmaceutically acceptable carrier, wherein the MEK compound of Formula I(M) and JAK-2 compound of Formula I(J) are as defined in the specification.

METHODS OF USING MEK INHIBITORS

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Page/Page column 340-341, (2008/12/06)

The present invention provides methods of treating cancer by administering a compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments.

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