1035389-11-7

Basic information

• Product Name: 4-tert-butoxycarbonylamino-4-(5-phenyl-1H-imidazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-tert-butoxycarbonylamino-4-(5-phenyl-1H-imidazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 1035389-11-7
• Molecular Weight: 442.558
• Mol File: 1035389-11-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-tert-butoxycarbonylamino-4-(5-phenyl-1H-imidazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-butoxycarbonylamino-4-(5-phenyl-1H-imidazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester(1035389-11-7)
• EPA Substance Registry System: 4-tert-butoxycarbonylamino-4-(5-phenyl-1H-imidazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester(1035389-11-7)

Safety Data

• Hazardous Substances Data: 1035389-11-7(Hazardous Substances Data)

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 189321-65-1 1-(tert-butoxycarbonyl)-4-((tert-butoxycarbonyl)amino)piperidine-4-carboxylic acid 

Relevant articles and documents

SUBSTITUTED PIPERIDINES HAVING PROTEIN KINASE INHIBITING ACTIVITY

The invention provides PKA and PKB kinase-inhibiting compounds of the formula (I); or salts, solvates, tautomers or N-oxides thereof, wherein E is a five membered heteroaryl ring containing 1, 2, 3 or 4 heteroatoms selected from O, N and S provided that no more than 1 heteroatom may be other than N; q and r are each is 0 or 1; provided that q+r is 1 or 2; T is N or a group CR5; J1-J2 is N=C(R6), (R7)C=N, (R8)N- C(O), (R8)2C-C(O), N=N or (R7)C=C(R6); Q3 is a bond or a saturated C1-3 hydrocarbon linker group optionally substituted by fluorine and hydroxy; G is NR2R3, CN or OH; m and n are each 0 or 1, provided that m+n is 1 or 2, and provided also that m or n are each 0 when the adjacent ring member of ring E is S or O; R1a and R1b are the same or different and each is hydrogen or a substituent R10; or R1a and R1b together with the carbon atoms or heteroatoms to which they are attached form a 5 or 6-membered aryl or heteroaryl ring, wherein the aryl or heteroaryl rings are optionally substituted by one or more substituents R10; and R2, R3, R4, R5, R7, R6, R8, and R10 are as defined in the claims.